Evaluation of antioxidant effect of extracts of Symphyopappus casarettoi
The ethanolic extract of Symphyopappus casarettoi syn. Eupatorium casarettoi was partionated in hexanic, chloroformic and methanolic fractions. Extract and fractions were tested for their antioxidant activity in vitro and ex vivo assays. The methanolic fraction showed a higher antioxidant potential...
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| Veröffentlicht in: | Fitoterapia 2007-04, Vol.78 (3), p.232-234 |
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| container_title | Fitoterapia |
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| creator | Netto Benetti, Mara Regina Rudnicki, Martina Zanotto-Filho, Alfeu de Oliveira, Marcos Roberto Kurek, Andréa Gisiane Coitinho, Adriana Schwartsmann, Gilberto Moreira, José Cláudio Fonseca |
| description | The ethanolic extract of
Symphyopappus casarettoi syn.
Eupatorium casarettoi was partionated in hexanic, chloroformic and methanolic fractions. Extract and fractions were tested for their antioxidant activity in vitro and ex vivo assays. The methanolic fraction showed a higher antioxidant potential compared to the others fractions, which was correlated with its total phenol content. In addition, the ethanolic extract and the methanolic fraction attenuated ex vivo iron-induced cell death, quantified by lactate dehydrogenase leakage, and effectively protected against lipid damage induced by iron. These findings suggest that the ethanolic extract of
S. casarettoi inflorescence and its methanolic fraction have in vitro and ex vivo antioxidant properties. |
| doi_str_mv | 10.1016/j.fitote.2006.11.019 |
| format | Article |
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Symphyopappus casarettoi syn.
Eupatorium casarettoi was partionated in hexanic, chloroformic and methanolic fractions. Extract and fractions were tested for their antioxidant activity in vitro and ex vivo assays. The methanolic fraction showed a higher antioxidant potential compared to the others fractions, which was correlated with its total phenol content. In addition, the ethanolic extract and the methanolic fraction attenuated ex vivo iron-induced cell death, quantified by lactate dehydrogenase leakage, and effectively protected against lipid damage induced by iron. These findings suggest that the ethanolic extract of
S. casarettoi inflorescence and its methanolic fraction have in vitro and ex vivo antioxidant properties.</description><identifier>ISSN: 0367-326X</identifier><identifier>DOI: 10.1016/j.fitote.2006.11.019</identifier><identifier>PMID: 17382486</identifier><language>eng</language><publisher>Amsterdam: Elsevier B.V</publisher><subject>Antioxidants - administration & dosage ; Antioxidants - pharmacology ; Antioxidants - therapeutic use ; Antioxidat activity ; Apoptosis - drug effects ; Asteraceae ; Biological and medical sciences ; Cell death ; Dose-Response Relationship, Drug ; General pharmacology ; Humans ; Iron ; Lipid Peroxidation - drug effects ; Medical sciences ; Pharmacognosy. Homeopathy. Health food ; Pharmacology. Drug treatments ; Phytotherapy ; Plant Extracts - administration & dosage ; Plant Extracts - pharmacology ; Plant Extracts - therapeutic use ; Symphyopappus casarettoi syn. Eupatorium casarettoi ; Thiobarbituric Acid Reactive Substances - chemistry</subject><ispartof>Fitoterapia, 2007-04, Vol.78 (3), p.232-234</ispartof><rights>2007 Elsevier B.V.</rights><rights>2007 INIST-CNRS</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c390t-3645e192a8a497e7a55ea2c1045902f030ca775a5c31b2f321080befe36bdb593</citedby><cites>FETCH-LOGICAL-c390t-3645e192a8a497e7a55ea2c1045902f030ca775a5c31b2f321080befe36bdb593</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.fitote.2006.11.019$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=18696159$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17382486$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Netto Benetti, Mara Regina</creatorcontrib><creatorcontrib>Rudnicki, Martina</creatorcontrib><creatorcontrib>Zanotto-Filho, Alfeu</creatorcontrib><creatorcontrib>de Oliveira, Marcos Roberto</creatorcontrib><creatorcontrib>Kurek, Andréa Gisiane</creatorcontrib><creatorcontrib>Coitinho, Adriana</creatorcontrib><creatorcontrib>Schwartsmann, Gilberto</creatorcontrib><creatorcontrib>Moreira, José Cláudio Fonseca</creatorcontrib><title>Evaluation of antioxidant effect of extracts of Symphyopappus casarettoi</title><title>Fitoterapia</title><addtitle>Fitoterapia</addtitle><description>The ethanolic extract of
Symphyopappus casarettoi syn.
Eupatorium casarettoi was partionated in hexanic, chloroformic and methanolic fractions. Extract and fractions were tested for their antioxidant activity in vitro and ex vivo assays. The methanolic fraction showed a higher antioxidant potential compared to the others fractions, which was correlated with its total phenol content. In addition, the ethanolic extract and the methanolic fraction attenuated ex vivo iron-induced cell death, quantified by lactate dehydrogenase leakage, and effectively protected against lipid damage induced by iron. These findings suggest that the ethanolic extract of
S. casarettoi inflorescence and its methanolic fraction have in vitro and ex vivo antioxidant properties.</description><subject>Antioxidants - administration & dosage</subject><subject>Antioxidants - pharmacology</subject><subject>Antioxidants - therapeutic use</subject><subject>Antioxidat activity</subject><subject>Apoptosis - drug effects</subject><subject>Asteraceae</subject><subject>Biological and medical sciences</subject><subject>Cell death</subject><subject>Dose-Response Relationship, Drug</subject><subject>General pharmacology</subject><subject>Humans</subject><subject>Iron</subject><subject>Lipid Peroxidation - drug effects</subject><subject>Medical sciences</subject><subject>Pharmacognosy. Homeopathy. Health food</subject><subject>Pharmacology. 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Symphyopappus casarettoi syn.
Eupatorium casarettoi was partionated in hexanic, chloroformic and methanolic fractions. Extract and fractions were tested for their antioxidant activity in vitro and ex vivo assays. The methanolic fraction showed a higher antioxidant potential compared to the others fractions, which was correlated with its total phenol content. In addition, the ethanolic extract and the methanolic fraction attenuated ex vivo iron-induced cell death, quantified by lactate dehydrogenase leakage, and effectively protected against lipid damage induced by iron. These findings suggest that the ethanolic extract of
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| subjects | Antioxidants - administration & dosage Antioxidants - pharmacology Antioxidants - therapeutic use Antioxidat activity Apoptosis - drug effects Asteraceae Biological and medical sciences Cell death Dose-Response Relationship, Drug General pharmacology Humans Iron Lipid Peroxidation - drug effects Medical sciences Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Phytotherapy Plant Extracts - administration & dosage Plant Extracts - pharmacology Plant Extracts - therapeutic use Symphyopappus casarettoi syn. Eupatorium casarettoi Thiobarbituric Acid Reactive Substances - chemistry |
| title | Evaluation of antioxidant effect of extracts of Symphyopappus casarettoi |
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