Use of dye as tracer of drug release from medicated chewing gums

The evaluation of the potential use of a dye as indicator of in vivo drug release from a medicated chewing gum is described. The device is a three-layer tablet obtained by direct compression consisting of a gum core and two external protective soluble layers to prevent gum adhesion to the punches of...

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Veröffentlicht in:European journal of pharmaceutics and biopharmaceutics 2008-03, Vol.68 (3), p.811-817
Hauptverfasser: Ochoa, Evelyn, Maggi, Lauretta, Conti, Stefania, Conte, Ubaldo, Vergnault, Guy, Grenier, Pascal
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Sprache:eng
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