Myocardial Damage in High-risk Patients Undergoing Elective Endovascular or Open Infrarenal Abdominal Aortic Aneurysm Repair
Objective Dobutamine stress echocardiography (DSE) provides an objective assessment of the presence and extent of coronary artery disease. Therefore we compared cardiac outcome in patients at high-cardiac risk undergoing open or endovascular repair of infrarenal AAA using preoperative DSE results. M...
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Veröffentlicht in: | European journal of vascular and endovascular surgery 2007-05, Vol.33 (5), p.544-549 |
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creator | Schouten, O Dunkelgrun, M Feringa, H.H.H Kok, N.F.M Vidakovic, R Bax, J.J Poldermans, D |
description | Objective Dobutamine stress echocardiography (DSE) provides an objective assessment of the presence and extent of coronary artery disease. Therefore we compared cardiac outcome in patients at high-cardiac risk undergoing open or endovascular repair of infrarenal AAA using preoperative DSE results. Methods Consecutive patients with ≥3 cardiac risk factors (age >70 years, angina pectoris, myocardial infarction, heart failure, stroke, renal failure, and diabetes mellitus) undergoing infrarenal AAA repair were reviewed retrospectively. All underwent cardiac stress testing using DSE. Postoperatively data on troponin release and ECG were collected on day 1, 3, 7, before discharge, and on day 30. The main outcome measures were perioperative myocardial damage and myocardial infarction or cardiovascular death. Results All 77 patients (39 endovascular, 38 open) had a history of cardiac disease. The number and type of cardiac risk factors were similar in both groups. Also DSE results were similar: 55 vs 56%, 24 vs 28%, and 21 vs 18% had no, limited, or extensive stress induced myocardial ischemia respectively. The incidence of perioperative myocardial damage (47% vs 13%, p = 0.001) and the combination of myocardial infarction or cardiovascular death (13% vs 0%, p = 0.02) was significantly lower in patients receiving endovascular repair. Conclusion In patients with similar high cardiac risk, endovascular repair of infrarenal aortic aneurysms is associated with a reduced incidence of perioperative myocardial damage. |
doi_str_mv | 10.1016/j.ejvs.2006.11.028 |
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Therefore we compared cardiac outcome in patients at high-cardiac risk undergoing open or endovascular repair of infrarenal AAA using preoperative DSE results. Methods Consecutive patients with ≥3 cardiac risk factors (age >70 years, angina pectoris, myocardial infarction, heart failure, stroke, renal failure, and diabetes mellitus) undergoing infrarenal AAA repair were reviewed retrospectively. All underwent cardiac stress testing using DSE. Postoperatively data on troponin release and ECG were collected on day 1, 3, 7, before discharge, and on day 30. The main outcome measures were perioperative myocardial damage and myocardial infarction or cardiovascular death. Results All 77 patients (39 endovascular, 38 open) had a history of cardiac disease. The number and type of cardiac risk factors were similar in both groups. Also DSE results were similar: 55 vs 56%, 24 vs 28%, and 21 vs 18% had no, limited, or extensive stress induced myocardial ischemia respectively. The incidence of perioperative myocardial damage (47% vs 13%, p = 0.001) and the combination of myocardial infarction or cardiovascular death (13% vs 0%, p = 0.02) was significantly lower in patients receiving endovascular repair. Conclusion In patients with similar high cardiac risk, endovascular repair of infrarenal aortic aneurysms is associated with a reduced incidence of perioperative myocardial damage.</description><identifier>ISSN: 1078-5884</identifier><identifier>EISSN: 1532-2165</identifier><identifier>DOI: 10.1016/j.ejvs.2006.11.028</identifier><identifier>PMID: 17196849</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Abdominal aortic aneurysm ; Aged ; Aortic Aneurysm, Abdominal - diagnostic imaging ; Aortic Aneurysm, Abdominal - epidemiology ; Aortic Aneurysm, Abdominal - surgery ; Cardiac stress testing ; Echocardiography, Stress ; Elective Surgical Procedures ; Electrocardiography ; Endovascular ; Female ; Heart Diseases - epidemiology ; High risk ; Humans ; Male ; Myocardium - pathology ; Risk Factors ; Surgery ; Troponin T - blood ; Vascular Surgical Procedures</subject><ispartof>European journal of vascular and endovascular surgery, 2007-05, Vol.33 (5), p.544-549</ispartof><rights>Elsevier Ltd</rights><rights>2006 Elsevier Ltd</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c519t-5189c50d2e71d2c62f6683babe516b9b84464580a4273b9cdaa72c4ab82afdda3</citedby><cites>FETCH-LOGICAL-c519t-5189c50d2e71d2c62f6683babe516b9b84464580a4273b9cdaa72c4ab82afdda3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.ejvs.2006.11.028$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>314,780,784,3549,27923,27924,45994</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17196849$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Schouten, O</creatorcontrib><creatorcontrib>Dunkelgrun, M</creatorcontrib><creatorcontrib>Feringa, H.H.H</creatorcontrib><creatorcontrib>Kok, N.F.M</creatorcontrib><creatorcontrib>Vidakovic, R</creatorcontrib><creatorcontrib>Bax, J.J</creatorcontrib><creatorcontrib>Poldermans, D</creatorcontrib><title>Myocardial Damage in High-risk Patients Undergoing Elective Endovascular or Open Infrarenal Abdominal Aortic Aneurysm Repair</title><title>European journal of vascular and endovascular surgery</title><addtitle>Eur J Vasc Endovasc Surg</addtitle><description>Objective Dobutamine stress echocardiography (DSE) provides an objective assessment of the presence and extent of coronary artery disease. Therefore we compared cardiac outcome in patients at high-cardiac risk undergoing open or endovascular repair of infrarenal AAA using preoperative DSE results. Methods Consecutive patients with ≥3 cardiac risk factors (age >70 years, angina pectoris, myocardial infarction, heart failure, stroke, renal failure, and diabetes mellitus) undergoing infrarenal AAA repair were reviewed retrospectively. All underwent cardiac stress testing using DSE. Postoperatively data on troponin release and ECG were collected on day 1, 3, 7, before discharge, and on day 30. The main outcome measures were perioperative myocardial damage and myocardial infarction or cardiovascular death. Results All 77 patients (39 endovascular, 38 open) had a history of cardiac disease. The number and type of cardiac risk factors were similar in both groups. Also DSE results were similar: 55 vs 56%, 24 vs 28%, and 21 vs 18% had no, limited, or extensive stress induced myocardial ischemia respectively. The incidence of perioperative myocardial damage (47% vs 13%, p = 0.001) and the combination of myocardial infarction or cardiovascular death (13% vs 0%, p = 0.02) was significantly lower in patients receiving endovascular repair. Conclusion In patients with similar high cardiac risk, endovascular repair of infrarenal aortic aneurysms is associated with a reduced incidence of perioperative myocardial damage.</description><subject>Abdominal aortic aneurysm</subject><subject>Aged</subject><subject>Aortic Aneurysm, Abdominal - diagnostic imaging</subject><subject>Aortic Aneurysm, Abdominal - epidemiology</subject><subject>Aortic Aneurysm, Abdominal - surgery</subject><subject>Cardiac stress testing</subject><subject>Echocardiography, Stress</subject><subject>Elective Surgical Procedures</subject><subject>Electrocardiography</subject><subject>Endovascular</subject><subject>Female</subject><subject>Heart Diseases - epidemiology</subject><subject>High risk</subject><subject>Humans</subject><subject>Male</subject><subject>Myocardium - pathology</subject><subject>Risk Factors</subject><subject>Surgery</subject><subject>Troponin T - blood</subject><subject>Vascular Surgical Procedures</subject><issn>1078-5884</issn><issn>1532-2165</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kkGL1DAUx4so7rr6BTxITt5ak7RpUxBhWMfdhZUVdc_hNXkdM9sms0k7MOCHN90ZEDx4yjv8_z_I770se8towSirP2wL3O5jwSmtC8YKyuWz7JyJkuec1eJ5mmkjcyFldZa9inFLKRWsFC-zM9awtpZVe579_nrwGoKxMJDPMMIGiXXk2m5-5cHGB_INJotuiuTeGQwbb92GrAfUk90jWTvj9xD1PEAgPpC7HTpy4_oAAV0CrjrjR_s0-TBZTVYO53CII_mOO7DhdfaihyHim9N7kd1_Wf-8vM5v765uLle3uRasnXLBZKsFNRwbZriueV_XsuygQ8Hqru1kVdWVkBQq3pRdqw1Aw3UFneTQGwPlRfb-yN0F_zhjnNRoo8ZhAId-jqqhZSNlW6UgPwZ18DEG7NUu2BHCQTGqFudqqxbnanGuGFPJeSq9O9HnbkTzt3KSnAIfjwFMf9xbDCrqJFWjsSGZVMbb__M__VPXg3VWw_CAB4xbP4ekOCqmIldU_Vi2viyd1gnSpnv4AwlQqZs</recordid><startdate>20070501</startdate><enddate>20070501</enddate><creator>Schouten, O</creator><creator>Dunkelgrun, M</creator><creator>Feringa, H.H.H</creator><creator>Kok, N.F.M</creator><creator>Vidakovic, R</creator><creator>Bax, J.J</creator><creator>Poldermans, D</creator><general>Elsevier Ltd</general><scope>6I.</scope><scope>AAFTH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20070501</creationdate><title>Myocardial Damage in High-risk Patients Undergoing Elective Endovascular or Open Infrarenal Abdominal Aortic Aneurysm Repair</title><author>Schouten, O ; Dunkelgrun, M ; Feringa, H.H.H ; Kok, N.F.M ; Vidakovic, R ; Bax, J.J ; Poldermans, D</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c519t-5189c50d2e71d2c62f6683babe516b9b84464580a4273b9cdaa72c4ab82afdda3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Abdominal aortic aneurysm</topic><topic>Aged</topic><topic>Aortic Aneurysm, Abdominal - diagnostic imaging</topic><topic>Aortic Aneurysm, Abdominal - epidemiology</topic><topic>Aortic Aneurysm, Abdominal - surgery</topic><topic>Cardiac stress testing</topic><topic>Echocardiography, Stress</topic><topic>Elective Surgical Procedures</topic><topic>Electrocardiography</topic><topic>Endovascular</topic><topic>Female</topic><topic>Heart Diseases - epidemiology</topic><topic>High risk</topic><topic>Humans</topic><topic>Male</topic><topic>Myocardium - pathology</topic><topic>Risk Factors</topic><topic>Surgery</topic><topic>Troponin T - blood</topic><topic>Vascular Surgical Procedures</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Schouten, O</creatorcontrib><creatorcontrib>Dunkelgrun, M</creatorcontrib><creatorcontrib>Feringa, H.H.H</creatorcontrib><creatorcontrib>Kok, N.F.M</creatorcontrib><creatorcontrib>Vidakovic, R</creatorcontrib><creatorcontrib>Bax, J.J</creatorcontrib><creatorcontrib>Poldermans, D</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>European journal of vascular and endovascular surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Schouten, O</au><au>Dunkelgrun, M</au><au>Feringa, H.H.H</au><au>Kok, N.F.M</au><au>Vidakovic, R</au><au>Bax, J.J</au><au>Poldermans, D</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Myocardial Damage in High-risk Patients Undergoing Elective Endovascular or Open Infrarenal Abdominal Aortic Aneurysm Repair</atitle><jtitle>European journal of vascular and endovascular surgery</jtitle><addtitle>Eur J Vasc Endovasc Surg</addtitle><date>2007-05-01</date><risdate>2007</risdate><volume>33</volume><issue>5</issue><spage>544</spage><epage>549</epage><pages>544-549</pages><issn>1078-5884</issn><eissn>1532-2165</eissn><abstract>Objective Dobutamine stress echocardiography (DSE) provides an objective assessment of the presence and extent of coronary artery disease. Therefore we compared cardiac outcome in patients at high-cardiac risk undergoing open or endovascular repair of infrarenal AAA using preoperative DSE results. Methods Consecutive patients with ≥3 cardiac risk factors (age >70 years, angina pectoris, myocardial infarction, heart failure, stroke, renal failure, and diabetes mellitus) undergoing infrarenal AAA repair were reviewed retrospectively. All underwent cardiac stress testing using DSE. Postoperatively data on troponin release and ECG were collected on day 1, 3, 7, before discharge, and on day 30. The main outcome measures were perioperative myocardial damage and myocardial infarction or cardiovascular death. Results All 77 patients (39 endovascular, 38 open) had a history of cardiac disease. The number and type of cardiac risk factors were similar in both groups. Also DSE results were similar: 55 vs 56%, 24 vs 28%, and 21 vs 18% had no, limited, or extensive stress induced myocardial ischemia respectively. The incidence of perioperative myocardial damage (47% vs 13%, p = 0.001) and the combination of myocardial infarction or cardiovascular death (13% vs 0%, p = 0.02) was significantly lower in patients receiving endovascular repair. Conclusion In patients with similar high cardiac risk, endovascular repair of infrarenal aortic aneurysms is associated with a reduced incidence of perioperative myocardial damage.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>17196849</pmid><doi>10.1016/j.ejvs.2006.11.028</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Abdominal aortic aneurysm Aged Aortic Aneurysm, Abdominal - diagnostic imaging Aortic Aneurysm, Abdominal - epidemiology Aortic Aneurysm, Abdominal - surgery Cardiac stress testing Echocardiography, Stress Elective Surgical Procedures Electrocardiography Endovascular Female Heart Diseases - epidemiology High risk Humans Male Myocardium - pathology Risk Factors Surgery Troponin T - blood Vascular Surgical Procedures |
title | Myocardial Damage in High-risk Patients Undergoing Elective Endovascular or Open Infrarenal Abdominal Aortic Aneurysm Repair |
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