Myocardial Damage in High-risk Patients Undergoing Elective Endovascular or Open Infrarenal Abdominal Aortic Aneurysm Repair

Objective Dobutamine stress echocardiography (DSE) provides an objective assessment of the presence and extent of coronary artery disease. Therefore we compared cardiac outcome in patients at high-cardiac risk undergoing open or endovascular repair of infrarenal AAA using preoperative DSE results. M...

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Veröffentlicht in:European journal of vascular and endovascular surgery 2007-05, Vol.33 (5), p.544-549
Hauptverfasser: Schouten, O, Dunkelgrun, M, Feringa, H.H.H, Kok, N.F.M, Vidakovic, R, Bax, J.J, Poldermans, D
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container_end_page 549
container_issue 5
container_start_page 544
container_title European journal of vascular and endovascular surgery
container_volume 33
creator Schouten, O
Dunkelgrun, M
Feringa, H.H.H
Kok, N.F.M
Vidakovic, R
Bax, J.J
Poldermans, D
description Objective Dobutamine stress echocardiography (DSE) provides an objective assessment of the presence and extent of coronary artery disease. Therefore we compared cardiac outcome in patients at high-cardiac risk undergoing open or endovascular repair of infrarenal AAA using preoperative DSE results. Methods Consecutive patients with ≥3 cardiac risk factors (age >70 years, angina pectoris, myocardial infarction, heart failure, stroke, renal failure, and diabetes mellitus) undergoing infrarenal AAA repair were reviewed retrospectively. All underwent cardiac stress testing using DSE. Postoperatively data on troponin release and ECG were collected on day 1, 3, 7, before discharge, and on day 30. The main outcome measures were perioperative myocardial damage and myocardial infarction or cardiovascular death. Results All 77 patients (39 endovascular, 38 open) had a history of cardiac disease. The number and type of cardiac risk factors were similar in both groups. Also DSE results were similar: 55 vs 56%, 24 vs 28%, and 21 vs 18% had no, limited, or extensive stress induced myocardial ischemia respectively. The incidence of perioperative myocardial damage (47% vs 13%, p = 0.001) and the combination of myocardial infarction or cardiovascular death (13% vs 0%, p = 0.02) was significantly lower in patients receiving endovascular repair. Conclusion In patients with similar high cardiac risk, endovascular repair of infrarenal aortic aneurysms is associated with a reduced incidence of perioperative myocardial damage.
doi_str_mv 10.1016/j.ejvs.2006.11.028
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Therefore we compared cardiac outcome in patients at high-cardiac risk undergoing open or endovascular repair of infrarenal AAA using preoperative DSE results. Methods Consecutive patients with ≥3 cardiac risk factors (age &gt;70 years, angina pectoris, myocardial infarction, heart failure, stroke, renal failure, and diabetes mellitus) undergoing infrarenal AAA repair were reviewed retrospectively. All underwent cardiac stress testing using DSE. Postoperatively data on troponin release and ECG were collected on day 1, 3, 7, before discharge, and on day 30. The main outcome measures were perioperative myocardial damage and myocardial infarction or cardiovascular death. Results All 77 patients (39 endovascular, 38 open) had a history of cardiac disease. The number and type of cardiac risk factors were similar in both groups. Also DSE results were similar: 55 vs 56%, 24 vs 28%, and 21 vs 18% had no, limited, or extensive stress induced myocardial ischemia respectively. The incidence of perioperative myocardial damage (47% vs 13%, p = 0.001) and the combination of myocardial infarction or cardiovascular death (13% vs 0%, p = 0.02) was significantly lower in patients receiving endovascular repair. Conclusion In patients with similar high cardiac risk, endovascular repair of infrarenal aortic aneurysms is associated with a reduced incidence of perioperative myocardial damage.</description><identifier>ISSN: 1078-5884</identifier><identifier>EISSN: 1532-2165</identifier><identifier>DOI: 10.1016/j.ejvs.2006.11.028</identifier><identifier>PMID: 17196849</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Abdominal aortic aneurysm ; Aged ; Aortic Aneurysm, Abdominal - diagnostic imaging ; Aortic Aneurysm, Abdominal - epidemiology ; Aortic Aneurysm, Abdominal - surgery ; Cardiac stress testing ; Echocardiography, Stress ; Elective Surgical Procedures ; Electrocardiography ; Endovascular ; Female ; Heart Diseases - epidemiology ; High risk ; Humans ; Male ; Myocardium - pathology ; Risk Factors ; Surgery ; Troponin T - blood ; Vascular Surgical Procedures</subject><ispartof>European journal of vascular and endovascular surgery, 2007-05, Vol.33 (5), p.544-549</ispartof><rights>Elsevier Ltd</rights><rights>2006 Elsevier Ltd</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c519t-5189c50d2e71d2c62f6683babe516b9b84464580a4273b9cdaa72c4ab82afdda3</citedby><cites>FETCH-LOGICAL-c519t-5189c50d2e71d2c62f6683babe516b9b84464580a4273b9cdaa72c4ab82afdda3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.ejvs.2006.11.028$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>314,780,784,3549,27923,27924,45994</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17196849$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Schouten, O</creatorcontrib><creatorcontrib>Dunkelgrun, M</creatorcontrib><creatorcontrib>Feringa, H.H.H</creatorcontrib><creatorcontrib>Kok, N.F.M</creatorcontrib><creatorcontrib>Vidakovic, R</creatorcontrib><creatorcontrib>Bax, J.J</creatorcontrib><creatorcontrib>Poldermans, D</creatorcontrib><title>Myocardial Damage in High-risk Patients Undergoing Elective Endovascular or Open Infrarenal Abdominal Aortic Aneurysm Repair</title><title>European journal of vascular and endovascular surgery</title><addtitle>Eur J Vasc Endovasc Surg</addtitle><description>Objective Dobutamine stress echocardiography (DSE) provides an objective assessment of the presence and extent of coronary artery disease. Therefore we compared cardiac outcome in patients at high-cardiac risk undergoing open or endovascular repair of infrarenal AAA using preoperative DSE results. Methods Consecutive patients with ≥3 cardiac risk factors (age &gt;70 years, angina pectoris, myocardial infarction, heart failure, stroke, renal failure, and diabetes mellitus) undergoing infrarenal AAA repair were reviewed retrospectively. All underwent cardiac stress testing using DSE. Postoperatively data on troponin release and ECG were collected on day 1, 3, 7, before discharge, and on day 30. The main outcome measures were perioperative myocardial damage and myocardial infarction or cardiovascular death. Results All 77 patients (39 endovascular, 38 open) had a history of cardiac disease. The number and type of cardiac risk factors were similar in both groups. Also DSE results were similar: 55 vs 56%, 24 vs 28%, and 21 vs 18% had no, limited, or extensive stress induced myocardial ischemia respectively. The incidence of perioperative myocardial damage (47% vs 13%, p = 0.001) and the combination of myocardial infarction or cardiovascular death (13% vs 0%, p = 0.02) was significantly lower in patients receiving endovascular repair. 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Therefore we compared cardiac outcome in patients at high-cardiac risk undergoing open or endovascular repair of infrarenal AAA using preoperative DSE results. Methods Consecutive patients with ≥3 cardiac risk factors (age &gt;70 years, angina pectoris, myocardial infarction, heart failure, stroke, renal failure, and diabetes mellitus) undergoing infrarenal AAA repair were reviewed retrospectively. All underwent cardiac stress testing using DSE. Postoperatively data on troponin release and ECG were collected on day 1, 3, 7, before discharge, and on day 30. The main outcome measures were perioperative myocardial damage and myocardial infarction or cardiovascular death. Results All 77 patients (39 endovascular, 38 open) had a history of cardiac disease. The number and type of cardiac risk factors were similar in both groups. Also DSE results were similar: 55 vs 56%, 24 vs 28%, and 21 vs 18% had no, limited, or extensive stress induced myocardial ischemia respectively. The incidence of perioperative myocardial damage (47% vs 13%, p = 0.001) and the combination of myocardial infarction or cardiovascular death (13% vs 0%, p = 0.02) was significantly lower in patients receiving endovascular repair. Conclusion In patients with similar high cardiac risk, endovascular repair of infrarenal aortic aneurysms is associated with a reduced incidence of perioperative myocardial damage.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>17196849</pmid><doi>10.1016/j.ejvs.2006.11.028</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record>
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subjects Abdominal aortic aneurysm
Aged
Aortic Aneurysm, Abdominal - diagnostic imaging
Aortic Aneurysm, Abdominal - epidemiology
Aortic Aneurysm, Abdominal - surgery
Cardiac stress testing
Echocardiography, Stress
Elective Surgical Procedures
Electrocardiography
Endovascular
Female
Heart Diseases - epidemiology
High risk
Humans
Male
Myocardium - pathology
Risk Factors
Surgery
Troponin T - blood
Vascular Surgical Procedures
title Myocardial Damage in High-risk Patients Undergoing Elective Endovascular or Open Infrarenal Abdominal Aortic Aneurysm Repair
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