Nearest neighbor parameters for inosine x uridine pairs in RNA duplexes

An enzyme family known as adenosine deaminases that act on RNA (ADARs) catalyzes adenosine deamination in RNA. ADARs act on RNA that is largely double-stranded and convert adenosine to inosine, resulting, in many cases, in an I x U pair. Thermodynamic parameters derived from optical melting studies...

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Veröffentlicht in:	Biochemistry (Easton) 2007-04, Vol.46 (15), p.4625-4634
Hauptverfasser:	Wright, Daniel J, Rice, Jamie L, Yanker, Dawn M, Znosko, Brent M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine - chemistry Algorithms Base Pairing Base Sequence Guanosine - chemistry Inosine - chemistry Molecular Structure Nucleic Acid Conformation Nucleic Acid Heteroduplexes - chemistry RNA - chemical synthesis RNA - chemistry Thermodynamics Uridine - chemistry
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