Prevalence of the metabolic syndrome and its components in Brazilian women with polycystic ovary syndrome
Objective To determine the prevalence of the metabolic syndrome (MetS) and its components in Brazilian women with polycystic ovary syndrome (PCOS). Design Cross-sectional study. Setting University Hospital, Federal University of Rio Grande do Norte, Natal-RN, Brazil. Patient(s) 102 women with PCOS b...
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| Veröffentlicht in: | Fertility and sterility 2008-03, Vol.89 (3), p.649-655 |
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| creator | Soares, Elvira Maria Mafaldo, M.D Azevedo, George Dantas, Ph.D Gadelha, Rafael Gonçalves Nóbrega, M.D Lemos, Telma Maria Araújo Moura, Ph.D Maranhão, Técia Maria Oliveira, Ph.D |
| description | Objective To determine the prevalence of the metabolic syndrome (MetS) and its components in Brazilian women with polycystic ovary syndrome (PCOS). Design Cross-sectional study. Setting University Hospital, Federal University of Rio Grande do Norte, Natal-RN, Brazil. Patient(s) 102 women with PCOS by the Rotterdam consensus criteria. Intervention(s) None. Main Outcome Measure(s) Clinical and biochemical parameters for MetS as defined by the National Cholesterol Education Program Adult Treatment Panel (NCEP ATP III). Result(s) The prevalence for individual components of MetS were high-density lipoprotein cholesterol level |
| doi_str_mv | 10.1016/j.fertnstert.2007.03.081 |
| format | Article |
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Design Cross-sectional study. Setting University Hospital, Federal University of Rio Grande do Norte, Natal-RN, Brazil. Patient(s) 102 women with PCOS by the Rotterdam consensus criteria. Intervention(s) None. Main Outcome Measure(s) Clinical and biochemical parameters for MetS as defined by the National Cholesterol Education Program Adult Treatment Panel (NCEP ATP III). Result(s) The prevalence for individual components of MetS were high-density lipoprotein cholesterol level <50 mg/dL in 69.6%, waist circumference ≥88 cm in 57.9%, triglyceride level ≥150 mg/dL in 31.7%, blood pressure ≥130/85 mm Hg in 18.6%, and fasting glucose concentrations ≥110 mg/dL in 2.9%. Three or more of these individual criteria were present in 29 (28.4%) of the patients. The prevalence of MetS increased with body mass index: 3.2%, 19.2% and 52.3% for normal, overweight, and obese women, respectively. Conclusion(s) These findings indicate that Brazilian women with PCOS have a high prevalence of MetS and its individual components, particularly a decreased high-density lipoprotein cholesterol level. Thus, these women are at increased risk of diabetes mellitus and cardiovascular disease.</description><identifier>ISSN: 0015-0282</identifier><identifier>EISSN: 1556-5653</identifier><identifier>DOI: 10.1016/j.fertnstert.2007.03.081</identifier><identifier>PMID: 17543961</identifier><identifier>CODEN: FESTAS</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Adult ; Biological and medical sciences ; Blood Glucose - metabolism ; Blood Pressure ; Brazil - epidemiology ; cardiovascular disease ; Cardiovascular Diseases - blood ; Cardiovascular Diseases - etiology ; Cardiovascular Diseases - physiopathology ; Cholesterol, HDL - blood ; Cross-Sectional Studies ; Diabetes Mellitus - blood ; Diabetes Mellitus - etiology ; Diabetes Mellitus - physiopathology ; Dyslipidemias - blood ; Dyslipidemias - epidemiology ; Female ; Female genital diseases ; Glucose Intolerance - blood ; Glucose Intolerance - epidemiology ; Gynecology. Andrology. Obstetrics ; Humans ; Hypertension - epidemiology ; Hypertension - physiopathology ; Internal Medicine ; Medical sciences ; Metabolic diseases ; Metabolic syndrome ; Metabolic Syndrome - blood ; Metabolic Syndrome - complications ; Metabolic Syndrome - epidemiology ; Metabolic Syndrome - physiopathology ; Miscellaneous ; Non tumoral diseases ; Obesity - blood ; Obesity - epidemiology ; Obstetrics and Gynecology ; Other metabolic disorders ; polycystic ovary syndrome ; Polycystic Ovary Syndrome - blood ; Polycystic Ovary Syndrome - complications ; Polycystic Ovary Syndrome - epidemiology ; Polycystic Ovary Syndrome - physiopathology ; Prevalence ; Risk Factors ; Triglycerides - blood</subject><ispartof>Fertility and sterility, 2008-03, Vol.89 (3), p.649-655</ispartof><rights>American Society for Reproductive Medicine</rights><rights>2008 American Society for Reproductive Medicine</rights><rights>2008 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c507t-430fba9a9a64b90f98016aa21ecc42893221b17b2fd1bb866fa603363b7bfb2a3</citedby><cites>FETCH-LOGICAL-c507t-430fba9a9a64b90f98016aa21ecc42893221b17b2fd1bb866fa603363b7bfb2a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0015028207008205$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27903,27904,65309</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=20200825$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17543961$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Soares, Elvira Maria Mafaldo, M.D</creatorcontrib><creatorcontrib>Azevedo, George Dantas, Ph.D</creatorcontrib><creatorcontrib>Gadelha, Rafael Gonçalves Nóbrega, M.D</creatorcontrib><creatorcontrib>Lemos, Telma Maria Araújo Moura, Ph.D</creatorcontrib><creatorcontrib>Maranhão, Técia Maria Oliveira, Ph.D</creatorcontrib><title>Prevalence of the metabolic syndrome and its components in Brazilian women with polycystic ovary syndrome</title><title>Fertility and sterility</title><addtitle>Fertil Steril</addtitle><description>Objective To determine the prevalence of the metabolic syndrome (MetS) and its components in Brazilian women with polycystic ovary syndrome (PCOS). Design Cross-sectional study. Setting University Hospital, Federal University of Rio Grande do Norte, Natal-RN, Brazil. Patient(s) 102 women with PCOS by the Rotterdam consensus criteria. Intervention(s) None. Main Outcome Measure(s) Clinical and biochemical parameters for MetS as defined by the National Cholesterol Education Program Adult Treatment Panel (NCEP ATP III). Result(s) The prevalence for individual components of MetS were high-density lipoprotein cholesterol level <50 mg/dL in 69.6%, waist circumference ≥88 cm in 57.9%, triglyceride level ≥150 mg/dL in 31.7%, blood pressure ≥130/85 mm Hg in 18.6%, and fasting glucose concentrations ≥110 mg/dL in 2.9%. Three or more of these individual criteria were present in 29 (28.4%) of the patients. The prevalence of MetS increased with body mass index: 3.2%, 19.2% and 52.3% for normal, overweight, and obese women, respectively. Conclusion(s) These findings indicate that Brazilian women with PCOS have a high prevalence of MetS and its individual components, particularly a decreased high-density lipoprotein cholesterol level. Thus, these women are at increased risk of diabetes mellitus and cardiovascular disease.</description><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Blood Glucose - metabolism</subject><subject>Blood Pressure</subject><subject>Brazil - epidemiology</subject><subject>cardiovascular disease</subject><subject>Cardiovascular Diseases - blood</subject><subject>Cardiovascular Diseases - etiology</subject><subject>Cardiovascular Diseases - physiopathology</subject><subject>Cholesterol, HDL - blood</subject><subject>Cross-Sectional Studies</subject><subject>Diabetes Mellitus - blood</subject><subject>Diabetes Mellitus - etiology</subject><subject>Diabetes Mellitus - physiopathology</subject><subject>Dyslipidemias - blood</subject><subject>Dyslipidemias - epidemiology</subject><subject>Female</subject><subject>Female genital diseases</subject><subject>Glucose Intolerance - blood</subject><subject>Glucose Intolerance - epidemiology</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Humans</subject><subject>Hypertension - epidemiology</subject><subject>Hypertension - physiopathology</subject><subject>Internal Medicine</subject><subject>Medical sciences</subject><subject>Metabolic diseases</subject><subject>Metabolic syndrome</subject><subject>Metabolic Syndrome - blood</subject><subject>Metabolic Syndrome - complications</subject><subject>Metabolic Syndrome - epidemiology</subject><subject>Metabolic Syndrome - physiopathology</subject><subject>Miscellaneous</subject><subject>Non tumoral diseases</subject><subject>Obesity - blood</subject><subject>Obesity - epidemiology</subject><subject>Obstetrics and Gynecology</subject><subject>Other metabolic disorders</subject><subject>polycystic ovary syndrome</subject><subject>Polycystic Ovary Syndrome - blood</subject><subject>Polycystic Ovary Syndrome - complications</subject><subject>Polycystic Ovary Syndrome - epidemiology</subject><subject>Polycystic Ovary Syndrome - physiopathology</subject><subject>Prevalence</subject><subject>Risk Factors</subject><subject>Triglycerides - blood</subject><issn>0015-0282</issn><issn>1556-5653</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNksGOFCEQhonRuLOrr2C46K3bAqah-2LibtQ12UQT9UyAhixjN4zAjGmfXjoz2U08GZKiDl_9VfwUQphAS4Dwt7vW2VRCLjW2FEC0wFroyRO0IV3Hm4537CnaAJCuAdrTC3SZ8w4AOBH0ObogotuygZMN8l-TParJBmNxdLjcWzzbonScvMF5CWOKs8UqjNiXjE2c9zHYUFMf8HVSf_zkVcC_K1SjL_d4H6fFLLnU8nhUaXkQeYGeOTVl-_J8X6EfHz98v7lt7r58-nzz_q4xHYjSbBk4rYZ6-FYP4Ia-PlgpSqwxW9oPjFKiidDUjUTrnnOnODDGmRbaaarYFXpz0t2n-Otgc5Gzz8ZOkwo2HrIUwITgPa1gfwJNijkn6-Q--bmOLAnI1Wa5k482y9VmCUxWm2vpq3OPg57t-Fh49rUCr8-AykZNLqlgfH7gKFS1nnaVuz5xtjpy9DbJbPz6GaNP1hQ5Rv8_07z7R8RMPvja96ddbN7FQwrVcUlkphLkt3Ut1q0AsQ4BHfsLNES31A</recordid><startdate>20080301</startdate><enddate>20080301</enddate><creator>Soares, Elvira Maria Mafaldo, M.D</creator><creator>Azevedo, George Dantas, Ph.D</creator><creator>Gadelha, Rafael Gonçalves Nóbrega, M.D</creator><creator>Lemos, Telma Maria Araújo Moura, Ph.D</creator><creator>Maranhão, Técia Maria Oliveira, Ph.D</creator><general>Elsevier Inc</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20080301</creationdate><title>Prevalence of the metabolic syndrome and its components in Brazilian women with polycystic ovary syndrome</title><author>Soares, Elvira Maria Mafaldo, M.D ; Azevedo, George Dantas, Ph.D ; Gadelha, Rafael Gonçalves Nóbrega, M.D ; Lemos, Telma Maria Araújo Moura, Ph.D ; Maranhão, Técia Maria Oliveira, Ph.D</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c507t-430fba9a9a64b90f98016aa21ecc42893221b17b2fd1bb866fa603363b7bfb2a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Blood Glucose - metabolism</topic><topic>Blood Pressure</topic><topic>Brazil - epidemiology</topic><topic>cardiovascular disease</topic><topic>Cardiovascular Diseases - blood</topic><topic>Cardiovascular Diseases - etiology</topic><topic>Cardiovascular Diseases - physiopathology</topic><topic>Cholesterol, HDL - blood</topic><topic>Cross-Sectional Studies</topic><topic>Diabetes Mellitus - blood</topic><topic>Diabetes Mellitus - etiology</topic><topic>Diabetes Mellitus - physiopathology</topic><topic>Dyslipidemias - blood</topic><topic>Dyslipidemias - epidemiology</topic><topic>Female</topic><topic>Female genital diseases</topic><topic>Glucose Intolerance - blood</topic><topic>Glucose Intolerance - epidemiology</topic><topic>Gynecology. Andrology. Obstetrics</topic><topic>Humans</topic><topic>Hypertension - epidemiology</topic><topic>Hypertension - physiopathology</topic><topic>Internal Medicine</topic><topic>Medical sciences</topic><topic>Metabolic diseases</topic><topic>Metabolic syndrome</topic><topic>Metabolic Syndrome - blood</topic><topic>Metabolic Syndrome - complications</topic><topic>Metabolic Syndrome - epidemiology</topic><topic>Metabolic Syndrome - physiopathology</topic><topic>Miscellaneous</topic><topic>Non tumoral diseases</topic><topic>Obesity - blood</topic><topic>Obesity - epidemiology</topic><topic>Obstetrics and Gynecology</topic><topic>Other metabolic disorders</topic><topic>polycystic ovary syndrome</topic><topic>Polycystic Ovary Syndrome - blood</topic><topic>Polycystic Ovary Syndrome - complications</topic><topic>Polycystic Ovary Syndrome - epidemiology</topic><topic>Polycystic Ovary Syndrome - physiopathology</topic><topic>Prevalence</topic><topic>Risk Factors</topic><topic>Triglycerides - blood</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Soares, Elvira Maria Mafaldo, M.D</creatorcontrib><creatorcontrib>Azevedo, George Dantas, Ph.D</creatorcontrib><creatorcontrib>Gadelha, Rafael Gonçalves Nóbrega, M.D</creatorcontrib><creatorcontrib>Lemos, Telma Maria Araújo Moura, Ph.D</creatorcontrib><creatorcontrib>Maranhão, Técia Maria Oliveira, Ph.D</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Fertility and sterility</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Soares, Elvira Maria Mafaldo, M.D</au><au>Azevedo, George Dantas, Ph.D</au><au>Gadelha, Rafael Gonçalves Nóbrega, M.D</au><au>Lemos, Telma Maria Araújo Moura, Ph.D</au><au>Maranhão, Técia Maria Oliveira, Ph.D</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prevalence of the metabolic syndrome and its components in Brazilian women with polycystic ovary syndrome</atitle><jtitle>Fertility and sterility</jtitle><addtitle>Fertil Steril</addtitle><date>2008-03-01</date><risdate>2008</risdate><volume>89</volume><issue>3</issue><spage>649</spage><epage>655</epage><pages>649-655</pages><issn>0015-0282</issn><eissn>1556-5653</eissn><coden>FESTAS</coden><abstract>Objective To determine the prevalence of the metabolic syndrome (MetS) and its components in Brazilian women with polycystic ovary syndrome (PCOS). Design Cross-sectional study. Setting University Hospital, Federal University of Rio Grande do Norte, Natal-RN, Brazil. Patient(s) 102 women with PCOS by the Rotterdam consensus criteria. Intervention(s) None. Main Outcome Measure(s) Clinical and biochemical parameters for MetS as defined by the National Cholesterol Education Program Adult Treatment Panel (NCEP ATP III). Result(s) The prevalence for individual components of MetS were high-density lipoprotein cholesterol level <50 mg/dL in 69.6%, waist circumference ≥88 cm in 57.9%, triglyceride level ≥150 mg/dL in 31.7%, blood pressure ≥130/85 mm Hg in 18.6%, and fasting glucose concentrations ≥110 mg/dL in 2.9%. Three or more of these individual criteria were present in 29 (28.4%) of the patients. The prevalence of MetS increased with body mass index: 3.2%, 19.2% and 52.3% for normal, overweight, and obese women, respectively. Conclusion(s) These findings indicate that Brazilian women with PCOS have a high prevalence of MetS and its individual components, particularly a decreased high-density lipoprotein cholesterol level. Thus, these women are at increased risk of diabetes mellitus and cardiovascular disease.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>17543961</pmid><doi>10.1016/j.fertnstert.2007.03.081</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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| source | MEDLINE; Elsevier ScienceDirect Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
| subjects | Adult Biological and medical sciences Blood Glucose - metabolism Blood Pressure Brazil - epidemiology cardiovascular disease Cardiovascular Diseases - blood Cardiovascular Diseases - etiology Cardiovascular Diseases - physiopathology Cholesterol, HDL - blood Cross-Sectional Studies Diabetes Mellitus - blood Diabetes Mellitus - etiology Diabetes Mellitus - physiopathology Dyslipidemias - blood Dyslipidemias - epidemiology Female Female genital diseases Glucose Intolerance - blood Glucose Intolerance - epidemiology Gynecology. Andrology. Obstetrics Humans Hypertension - epidemiology Hypertension - physiopathology Internal Medicine Medical sciences Metabolic diseases Metabolic syndrome Metabolic Syndrome - blood Metabolic Syndrome - complications Metabolic Syndrome - epidemiology Metabolic Syndrome - physiopathology Miscellaneous Non tumoral diseases Obesity - blood Obesity - epidemiology Obstetrics and Gynecology Other metabolic disorders polycystic ovary syndrome Polycystic Ovary Syndrome - blood Polycystic Ovary Syndrome - complications Polycystic Ovary Syndrome - epidemiology Polycystic Ovary Syndrome - physiopathology Prevalence Risk Factors Triglycerides - blood |
| title | Prevalence of the metabolic syndrome and its components in Brazilian women with polycystic ovary syndrome |
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