Mucolytics in cystic fibrosis

Summary Mucus accumulation in the lower airways is a key feature of cystic fibrosis (CF) lung disease. The major component of mucus in CF is not mucin derived from mucus producing cells but rather pus that includes viscous material such as polymerized DNA derived from degraded neutrophils. This has...

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Veröffentlicht in:	Paediatric respiratory reviews 2007-03, Vol.8 (1), p.24-29
Hauptverfasser:	Henke, Markus O, Ratjen, Felix
Format:	Artikel
Sprache:	eng
Schlagworte:	cystic fibrosis Cystic Fibrosis - drug therapy dornase alfa Expectorants - therapeutic use gelsolin Humans hypertonic saline mucolytics N-acetylcysteine Pediatrics Pulmonary/Respiratory thymosin
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