Two-Photon Fluorescent Probes for Acidic Vesicles in Live Cells and Tissue

Two-Photon Fluorescent Probes for Acidic Vesicles in Live Cells and Tissue

Move with the groove: Two‐photon fluorescent pH probes and a two‐photon lysotracker (AL1) can visualize acidic vesicles in live cells and living tissue for a long period of time without mistargeting and photobleaching problems. Using AL1, vesicles can be tracked in real time (see picture).

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Bibliographische Detailangaben
Veröffentlicht in:Angewandte Chemie (International ed.) 2008-03, Vol.47 (12), p.2231-2234
Hauptverfasser: Kim, Hwan Myung, An, Myoung Jin, Hong, Jin Hee, Jeong, Byeong Ha, Kwon, Ohyun, Hyon, Ju-Yong, Hong, Seok-Cheol, Lee, Kyoung J, Cho, Bong Rae
Format: Artikel
Sprache:eng
Schlagworte:
acidity
Acids - chemistry
Animals
Cell Survival
Fluorescent Dyes - chemistry
fluorescent probes
Hippocampus - metabolism
live tissue
Molecular Structure
Photochemistry
Photons
Rats
two-photon microscopy
vesicles
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Beschreibung
Zusammenfassung:Move with the groove: Two‐photon fluorescent pH probes and a two‐photon lysotracker (AL1) can visualize acidic vesicles in live cells and living tissue for a long period of time without mistargeting and photobleaching problems. Using AL1, vesicles can be tracked in real time (see picture).
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.200704586