Pd-Catalyzed Aryl Amination Mediated by Well Defined, N-Heterocyclic Carbene (NHC)-Pd Precatalysts, PEPPSI

Pd–N‐heterocyclic carbene (NHC)‐catalyzed Buchwald–Hartwig amination protocols mediated by Pd–PEPPSI precatalysts is described. These protocols provide access to a range of hindered and functionalized drug‐like aryl amines in high yield with both electron‐deficient and electron‐rich aryl‐ and hetero...

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Veröffentlicht in:	Chemistry : a European journal 2008-03, Vol.14 (8), p.2443-2452
Hauptverfasser:	Organ, Michael G., Abdel-Hadi, Mirvat, Avola, Stephanie, Dubovyk, Igor, Hadei, Niloufar, Kantchev, Eric Assen B., O'Brien, Christopher J., Sayah, Mahmoud, Valente, Cory
Format:	Artikel
Sprache:	eng
Schlagworte:	Amination anilines asymmetric catalysis carbenes Catalysis Heterocyclic Compounds - chemistry Hydrocarbons - chemistry Ligands Methane - analogs & derivatives Methane - chemistry palladium Palladium - chemistry Phosphines - chemistry Temperature
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