Treatment with total alkaloids from Radix Linderae reduces inflammation and joint destruction in type II collagen-induced model for rheumatoid arthritis

Radix Linderae, the dry roots of Lindera aggregata (Sims) Kosterm., is frequently used in traditional Chinese medicine. It contains alkaloids, volatile oils and sesquiterpene esters. In the present study, we investigated the therapeutic potential and underlying mechanisms of the total alkaloids from...

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Veröffentlicht in:	Journal of ethnopharmacology 2007-05, Vol.111 (2), p.322-328
Hauptverfasser:	Wang, Chan, Dai, Yue, Yang, Jian, Chou, Guixin, Wang, Changhong, Wang, Zhengtao
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkaloid alkaloids Alkaloids - pharmacology Alkaloids - therapeutic use Animals anti-inflammatory agents Arthritis Arthritis, Rheumatoid - drug therapy Arthritis, Rheumatoid - pathology bioassays Biological and medical sciences biosynthesis chemical constituents of plants Chickens Collagen Collagen Type II - metabolism Disease Models, Animal Dose-Response Relationship, Drug ethnobotany General pharmacology Herbal Medicine herbal medicines inflammation Inflammation - drug therapy joint diseases Joints - drug effects Joints - pathology Lindera Lindera - chemistry Lindera aggregata Male Medical sciences medicinal plants medicinal properties Medicine, Chinese Traditional Mice Mice, Inbred ICR Oriental traditional medicine Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments plant extracts Plant Roots - chemistry Radix Linderae rheumatoid arthritis roots
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