Matrix-assisted pulsed laser evaporation of poly(D,L-lactide) for biomedical applications: effect of near infrared radiation
The deposition of thin films of poly(D,L-lactide) (PDLLA) by using the matrix-assisted pulsed laser evaporation (MAPLE) technique is investigated. PDLLA is a highly biocompatible and biodegradable polymer, with wide applicability in the biomedical field. The laser wavelength used in the MAPLE proces...
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| Veröffentlicht in: | Journal of Biomedical Optics 2008-01, Vol.13 (1), p.014028-014026 |
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| container_title | Journal of Biomedical Optics |
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| creator | Califano, Valeria Bloisi, Francesco Vicari, Luciano R. M Bretcanu, Oana Boccaccini, Aldo R |
| description | The deposition of thin films of poly(D,L-lactide) (PDLLA) by using the matrix-assisted pulsed laser evaporation (MAPLE) technique is investigated. PDLLA is a highly biocompatible and biodegradable polymer, with wide applicability in the biomedical field. The laser wavelength used in the MAPLE process is optimized to obtain a good-quality deposition. The structure of the polymer film is analyzed by Fourier transform infrared spectroscopy (FTIR). It is found that the chemical structure of PDLLA undergoes little or no damage during deposition with near-infrared laser radiation
. It is thus confirmed that at this wavelength, the MAPLE technique can be applied for fragile biopolymer molecules, which are easily damaged by other laser radiations (UV radiation). This method allows future development of tailored polymer coatings for biomedical applications. |
| doi_str_mv | 10.1117/1.2830660 |
| format | Article |
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. It is thus confirmed that at this wavelength, the MAPLE technique can be applied for fragile biopolymer molecules, which are easily damaged by other laser radiations (UV radiation). 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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | biopolymers Coated Materials, Biocompatible - chemistry Coated Materials, Biocompatible - radiation effects coatings Crystallization - methods Damage Deposition Evaporation Fourier transforms Gases - chemistry Gases - radiation effects Infrared Rays Infrared spectroscopy Lasers Materials Testing matrix-assisted pulsed laser evaporation poly(D,L-lactide) Polyesters - chemistry Polyesters - radiation effects Pulsed lasers thin films Wavelengths |
| title | Matrix-assisted pulsed laser evaporation of poly(D,L-lactide) for biomedical applications: effect of near infrared radiation |
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