Modified‐Release Subantimicrobial Dose Doxycycline Enhances Scaling and Root Planing in Subjects With Periodontal Disease

Background: Previous studies showed that adjunctive subantimicrobial dose doxycycline (SDD; 20 mg, twice daily) provides significant clinical benefits to scaling and root planing (SRP). A modified‐release SDD formulation containing 40 mg doxycycline (SDD‐40) to be taken once daily has been developed...

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Veröffentlicht in:	Journal of periodontology (1970) 2008-03, Vol.79 (3), p.440-452
Hauptverfasser:	Preshaw, Philip M., Novak, M. John, Mellonig, James, Magnusson, Ingvar, Polson, Alan, Giannobile, William V., Rowland, Randal W., Thomas, John, Walker, Clay, Dawson, Dolphus R., Sharkey, Dennis, Bradshaw, Mark H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Topical Adult Aged Aged, 80 and over Analysis of Variance Anti-Bacterial Agents - administration & dosage Bacteria, Anaerobic - isolation & purification Biological and medical sciences Colony Count, Microbial Combined Modality Therapy Dental Plaque - microbiology Dental Scaling Dentistry Double-Blind Method Double‐masked method Doxycycline - administration & dosage doxycycline/therapeutic use Facial bones, jaws, teeth, parodontium: diseases, semeiology Female Humans Linear Models Male Medical sciences Middle Aged multicenter Non tumoral diseases Otorhinolaryngology. Stomatology Periodontal Index Periodontitis - drug therapy Periodontitis - therapy Statistics, Nonparametric
Online-Zugang:	Volltext
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