Two New Triterpenoids and a Steroidal Glycoside from the Aerial Parts of Ocimum basilicum

Studies on the chemical constituents of the aerial parts of Ocimum basilicum have led to the isolation of three new compounds, basilol (1), ocimol (2), and basilimoside (3), along with two known constituents betulinic acid and oleanolic acid. The structures of the new constituents have been elucidat...

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Veröffentlicht in:Chemical & Pharmaceutical Bulletin 2007, Vol.55(4), pp.516-519
Hauptverfasser: Siddiqui, Bina Shaheen, Aslam, Huma, Ali, Syed Tariq, Begum, Sabira, Khatoon, Nasima
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Sprache:eng
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Zusammenfassung:Studies on the chemical constituents of the aerial parts of Ocimum basilicum have led to the isolation of three new compounds, basilol (1), ocimol (2), and basilimoside (3), along with two known constituents betulinic acid and oleanolic acid. The structures of the new constituents have been elucidated through spectral studies including 2D-NMR experiments (HMQC, HMBC, COSY, NOESY, and J-resolved) and chemical transformation, as p-formylphenyl 3β-hydroxyolean-12-en-28-oate (1), 2-methoxy-4-carbomethoxyphenyl 3β-hydroxy-lup-20(29)-en-28-oate (2), and (22E)-24ξ-ethyl-25-methylcholesta-5,22-diene-3β-ol-3-O-D-glucopyranoside (3).
ISSN:0009-2363
1347-5223
DOI:10.1248/cpb.55.516