Psychosocial status predicts mortality in patients with life-threatening ventricular arrhythmias
Background Quality-of-life (QoL) instruments evaluate various aspects of physical, mental, and emotional health, but how these psychosocial characteristics impact long-term outcome after cardiac arrest and ventricular tachycardia (VT) is unknown. Objective The purpose of this study was to evaluate t...
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| Veröffentlicht in: | Heart rhythm 2008-03, Vol.5 (3), p.361-365 |
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| creator | Steinberg, Jonathan S., MD, FACC, FHRS Joshi, Sandeep, MD Schron, Eleanor B., MS, RN Powell, Judy, BSN Hallstrom, Alfred, PhD McBurnie, MaryAnn, PhD |
| description | Background Quality-of-life (QoL) instruments evaluate various aspects of physical, mental, and emotional health, but how these psychosocial characteristics impact long-term outcome after cardiac arrest and ventricular tachycardia (VT) is unknown. Objective The purpose of this study was to evaluate the relationship of baseline QoL scores with long-term survival of patients enrolled in the Antiarrhythmics Versus Implantable Defibrillators (AVID) trial. Methods Formal QoL measures included SF-36 mental and physical components, Patient Concerns Checklist, and Ferrans and Powers Quality-of-Life Index–Cardiac Version. Multivariate Cox regression was used to assess the association of survival and these measures, adjusting for index arrhythmia type, gender, race, age, ejection fraction, history of congestive heart failure, antiarrhythmic therapy, and beta-blocker use. Results During mean follow-up of 546 ± 356 days, 129 deaths occurred among 740 patients. Higher baseline SF-36 physical summary scores ( P |
| doi_str_mv | 10.1016/j.hrthm.2007.11.010 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_70354131</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S1547527107011058</els_id><sourcerecordid>70354131</sourcerecordid><originalsourceid>FETCH-LOGICAL-c412t-a1ba2d5aa07571e6446e8f8b25b5beffdd853af44386250e14ed7cb1fdb13fae3</originalsourceid><addsrcrecordid>eNqFkUFv1DAQhS0Eou3CL0BCOXFL8NhxnB5AQhVQpEpUAs7GccbEi5MsttMq_x6HXQmpl57GGr839vuGkFdAK6DQvN1XQ0jDWDFKZQVQUaBPyDkI0ZS8lfB0O9eyFEzCGbmIcU8pu2wof07OoOXAxSU7Jz9v42qGOc7GaV_EpNMSi0PA3pkUi3EOSXuX1sJNxUEnh1Pu3rs0FN5ZLNMQUCec3PSruMt3wZnF61DoEIY1_83p-II8s9pHfHmqO_Lj08fvV9flzdfPX64-3JSmBpZKDZ1mvdCaSiEBm7pusLVtx0QnOrS271vBta1r3jZMUIQae2k6sH0H3GrkO_LmOPcQ5j8LxqRGFw16ryecl6gk5aKGHHtH-FFowhxjQKsOwY06rAqo2sCqvfoHVm1gFYDKYLPr9Wn80o3Y__ecSGbBu6MAc8g7h0FFk3GZTDKgSaqf3SMPvH_gN95Nzmj_G1eM-3kJU-anQEWmqPq27XZbLZUUgIqW_wXC4aMV</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>70354131</pqid></control><display><type>article</type><title>Psychosocial status predicts mortality in patients with life-threatening ventricular arrhythmias</title><source>MEDLINE</source><source>Access via ScienceDirect (Elsevier)</source><creator>Steinberg, Jonathan S., MD, FACC, FHRS ; Joshi, Sandeep, MD ; Schron, Eleanor B., MS, RN ; Powell, Judy, BSN ; Hallstrom, Alfred, PhD ; McBurnie, MaryAnn, PhD</creator><creatorcontrib>Steinberg, Jonathan S., MD, FACC, FHRS ; Joshi, Sandeep, MD ; Schron, Eleanor B., MS, RN ; Powell, Judy, BSN ; Hallstrom, Alfred, PhD ; McBurnie, MaryAnn, PhD ; AVID Investigators</creatorcontrib><description>Background Quality-of-life (QoL) instruments evaluate various aspects of physical, mental, and emotional health, but how these psychosocial characteristics impact long-term outcome after cardiac arrest and ventricular tachycardia (VT) is unknown. Objective The purpose of this study was to evaluate the relationship of baseline QoL scores with long-term survival of patients enrolled in the Antiarrhythmics Versus Implantable Defibrillators (AVID) trial. Methods Formal QoL measures included SF-36 mental and physical components, Patient Concerns Checklist, and Ferrans and Powers Quality-of-Life Index–Cardiac Version. Multivariate Cox regression was used to assess the association of survival and these measures, adjusting for index arrhythmia type, gender, race, age, ejection fraction, history of congestive heart failure, antiarrhythmic therapy, and beta-blocker use. Results During mean follow-up of 546 ± 356 days, 129 deaths occurred among 740 patients. Higher baseline SF-36 physical summary scores ( P <.001), higher baseline QoL Index summary scores ( P = .015), and lower baseline Patient Concerns Checklist summary scores ( P = .047) were associated with longer survival, even after adjustment for clinical variables. When QoL measures were examined simultaneously, only the SF-36 physical summary score remained significant ( P = .002). Conclusion During recovery after sustained VT or cardiac arrest, formal baseline QoL assessment provides important prognostic information independent of traditional clinical data.</description><identifier>ISSN: 1547-5271</identifier><identifier>EISSN: 1556-3871</identifier><identifier>DOI: 10.1016/j.hrthm.2007.11.010</identifier><identifier>PMID: 18313592</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Aged ; Antiarrhythmic Versus Implantable Defibrillators trial ; Antiarrhythmics ; Cardiac arrest ; Cardiovascular ; Chi-Square Distribution ; Defibrillation ; Defibrillators, Implantable ; Female ; Heart Arrest - mortality ; Heart Arrest - psychology ; Heart Arrest - therapy ; Humans ; Male ; Middle Aged ; Predictive Value of Tests ; Prognosis ; Proportional Hazards Models ; Prospective Studies ; Quality of Life ; Risk Factors ; Tachyarrhythmias ; Tachycardia, Ventricular - mortality ; Tachycardia, Ventricular - psychology ; Tachycardia, Ventricular - therapy</subject><ispartof>Heart rhythm, 2008-03, Vol.5 (3), p.361-365</ispartof><rights>Heart Rhythm Society</rights><rights>2008 Heart Rhythm Society</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c412t-a1ba2d5aa07571e6446e8f8b25b5beffdd853af44386250e14ed7cb1fdb13fae3</citedby><cites>FETCH-LOGICAL-c412t-a1ba2d5aa07571e6446e8f8b25b5beffdd853af44386250e14ed7cb1fdb13fae3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.hrthm.2007.11.010$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18313592$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Steinberg, Jonathan S., MD, FACC, FHRS</creatorcontrib><creatorcontrib>Joshi, Sandeep, MD</creatorcontrib><creatorcontrib>Schron, Eleanor B., MS, RN</creatorcontrib><creatorcontrib>Powell, Judy, BSN</creatorcontrib><creatorcontrib>Hallstrom, Alfred, PhD</creatorcontrib><creatorcontrib>McBurnie, MaryAnn, PhD</creatorcontrib><creatorcontrib>AVID Investigators</creatorcontrib><title>Psychosocial status predicts mortality in patients with life-threatening ventricular arrhythmias</title><title>Heart rhythm</title><addtitle>Heart Rhythm</addtitle><description>Background Quality-of-life (QoL) instruments evaluate various aspects of physical, mental, and emotional health, but how these psychosocial characteristics impact long-term outcome after cardiac arrest and ventricular tachycardia (VT) is unknown. Objective The purpose of this study was to evaluate the relationship of baseline QoL scores with long-term survival of patients enrolled in the Antiarrhythmics Versus Implantable Defibrillators (AVID) trial. Methods Formal QoL measures included SF-36 mental and physical components, Patient Concerns Checklist, and Ferrans and Powers Quality-of-Life Index–Cardiac Version. Multivariate Cox regression was used to assess the association of survival and these measures, adjusting for index arrhythmia type, gender, race, age, ejection fraction, history of congestive heart failure, antiarrhythmic therapy, and beta-blocker use. Results During mean follow-up of 546 ± 356 days, 129 deaths occurred among 740 patients. Higher baseline SF-36 physical summary scores ( P <.001), higher baseline QoL Index summary scores ( P = .015), and lower baseline Patient Concerns Checklist summary scores ( P = .047) were associated with longer survival, even after adjustment for clinical variables. When QoL measures were examined simultaneously, only the SF-36 physical summary score remained significant ( P = .002). Conclusion During recovery after sustained VT or cardiac arrest, formal baseline QoL assessment provides important prognostic information independent of traditional clinical data.</description><subject>Aged</subject><subject>Antiarrhythmic Versus Implantable Defibrillators trial</subject><subject>Antiarrhythmics</subject><subject>Cardiac arrest</subject><subject>Cardiovascular</subject><subject>Chi-Square Distribution</subject><subject>Defibrillation</subject><subject>Defibrillators, Implantable</subject><subject>Female</subject><subject>Heart Arrest - mortality</subject><subject>Heart Arrest - psychology</subject><subject>Heart Arrest - therapy</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Predictive Value of Tests</subject><subject>Prognosis</subject><subject>Proportional Hazards Models</subject><subject>Prospective Studies</subject><subject>Quality of Life</subject><subject>Risk Factors</subject><subject>Tachyarrhythmias</subject><subject>Tachycardia, Ventricular - mortality</subject><subject>Tachycardia, Ventricular - psychology</subject><subject>Tachycardia, Ventricular - therapy</subject><issn>1547-5271</issn><issn>1556-3871</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkUFv1DAQhS0Eou3CL0BCOXFL8NhxnB5AQhVQpEpUAs7GccbEi5MsttMq_x6HXQmpl57GGr839vuGkFdAK6DQvN1XQ0jDWDFKZQVQUaBPyDkI0ZS8lfB0O9eyFEzCGbmIcU8pu2wof07OoOXAxSU7Jz9v42qGOc7GaV_EpNMSi0PA3pkUi3EOSXuX1sJNxUEnh1Pu3rs0FN5ZLNMQUCec3PSruMt3wZnF61DoEIY1_83p-II8s9pHfHmqO_Lj08fvV9flzdfPX64-3JSmBpZKDZ1mvdCaSiEBm7pusLVtx0QnOrS271vBta1r3jZMUIQae2k6sH0H3GrkO_LmOPcQ5j8LxqRGFw16ryecl6gk5aKGHHtH-FFowhxjQKsOwY06rAqo2sCqvfoHVm1gFYDKYLPr9Wn80o3Y__ecSGbBu6MAc8g7h0FFk3GZTDKgSaqf3SMPvH_gN95Nzmj_G1eM-3kJU-anQEWmqPq27XZbLZUUgIqW_wXC4aMV</recordid><startdate>20080301</startdate><enddate>20080301</enddate><creator>Steinberg, Jonathan S., MD, FACC, FHRS</creator><creator>Joshi, Sandeep, MD</creator><creator>Schron, Eleanor B., MS, RN</creator><creator>Powell, Judy, BSN</creator><creator>Hallstrom, Alfred, PhD</creator><creator>McBurnie, MaryAnn, PhD</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20080301</creationdate><title>Psychosocial status predicts mortality in patients with life-threatening ventricular arrhythmias</title><author>Steinberg, Jonathan S., MD, FACC, FHRS ; Joshi, Sandeep, MD ; Schron, Eleanor B., MS, RN ; Powell, Judy, BSN ; Hallstrom, Alfred, PhD ; McBurnie, MaryAnn, PhD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c412t-a1ba2d5aa07571e6446e8f8b25b5beffdd853af44386250e14ed7cb1fdb13fae3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Aged</topic><topic>Antiarrhythmic Versus Implantable Defibrillators trial</topic><topic>Antiarrhythmics</topic><topic>Cardiac arrest</topic><topic>Cardiovascular</topic><topic>Chi-Square Distribution</topic><topic>Defibrillation</topic><topic>Defibrillators, Implantable</topic><topic>Female</topic><topic>Heart Arrest - mortality</topic><topic>Heart Arrest - psychology</topic><topic>Heart Arrest - therapy</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Predictive Value of Tests</topic><topic>Prognosis</topic><topic>Proportional Hazards Models</topic><topic>Prospective Studies</topic><topic>Quality of Life</topic><topic>Risk Factors</topic><topic>Tachyarrhythmias</topic><topic>Tachycardia, Ventricular - mortality</topic><topic>Tachycardia, Ventricular - psychology</topic><topic>Tachycardia, Ventricular - therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Steinberg, Jonathan S., MD, FACC, FHRS</creatorcontrib><creatorcontrib>Joshi, Sandeep, MD</creatorcontrib><creatorcontrib>Schron, Eleanor B., MS, RN</creatorcontrib><creatorcontrib>Powell, Judy, BSN</creatorcontrib><creatorcontrib>Hallstrom, Alfred, PhD</creatorcontrib><creatorcontrib>McBurnie, MaryAnn, PhD</creatorcontrib><creatorcontrib>AVID Investigators</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Heart rhythm</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Steinberg, Jonathan S., MD, FACC, FHRS</au><au>Joshi, Sandeep, MD</au><au>Schron, Eleanor B., MS, RN</au><au>Powell, Judy, BSN</au><au>Hallstrom, Alfred, PhD</au><au>McBurnie, MaryAnn, PhD</au><aucorp>AVID Investigators</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Psychosocial status predicts mortality in patients with life-threatening ventricular arrhythmias</atitle><jtitle>Heart rhythm</jtitle><addtitle>Heart Rhythm</addtitle><date>2008-03-01</date><risdate>2008</risdate><volume>5</volume><issue>3</issue><spage>361</spage><epage>365</epage><pages>361-365</pages><issn>1547-5271</issn><eissn>1556-3871</eissn><abstract>Background Quality-of-life (QoL) instruments evaluate various aspects of physical, mental, and emotional health, but how these psychosocial characteristics impact long-term outcome after cardiac arrest and ventricular tachycardia (VT) is unknown. Objective The purpose of this study was to evaluate the relationship of baseline QoL scores with long-term survival of patients enrolled in the Antiarrhythmics Versus Implantable Defibrillators (AVID) trial. Methods Formal QoL measures included SF-36 mental and physical components, Patient Concerns Checklist, and Ferrans and Powers Quality-of-Life Index–Cardiac Version. Multivariate Cox regression was used to assess the association of survival and these measures, adjusting for index arrhythmia type, gender, race, age, ejection fraction, history of congestive heart failure, antiarrhythmic therapy, and beta-blocker use. Results During mean follow-up of 546 ± 356 days, 129 deaths occurred among 740 patients. Higher baseline SF-36 physical summary scores ( P <.001), higher baseline QoL Index summary scores ( P = .015), and lower baseline Patient Concerns Checklist summary scores ( P = .047) were associated with longer survival, even after adjustment for clinical variables. When QoL measures were examined simultaneously, only the SF-36 physical summary score remained significant ( P = .002). Conclusion During recovery after sustained VT or cardiac arrest, formal baseline QoL assessment provides important prognostic information independent of traditional clinical data.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>18313592</pmid><doi>10.1016/j.hrthm.2007.11.010</doi><tpages>5</tpages></addata></record> |
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| subjects | Aged Antiarrhythmic Versus Implantable Defibrillators trial Antiarrhythmics Cardiac arrest Cardiovascular Chi-Square Distribution Defibrillation Defibrillators, Implantable Female Heart Arrest - mortality Heart Arrest - psychology Heart Arrest - therapy Humans Male Middle Aged Predictive Value of Tests Prognosis Proportional Hazards Models Prospective Studies Quality of Life Risk Factors Tachyarrhythmias Tachycardia, Ventricular - mortality Tachycardia, Ventricular - psychology Tachycardia, Ventricular - therapy |
| title | Psychosocial status predicts mortality in patients with life-threatening ventricular arrhythmias |
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