Stimulatory Activity of Lignans from Machilus thunbergii on Osteoblast Differentiation

Phytoestrogens are naturally occurring compounds exerting estrogenic activity, and include isoflavonoids, flavonoids and lignans. In the present study, we evaluated the stimulating activity of six lignans, meso-dihydroguaiaretic acid, nordihydroguaiaretic acid, machilin A, guaiacin, isoguaiacin and...

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Veröffentlicht in:	Biological & Pharmaceutical Bulletin 2007, Vol.30(4), pp.814-817
Hauptverfasser:	Lee, Mi Kyeong, Yang, Hyekyung, Ma, Choong Je, Kim, Young Choong
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkaline Phosphatase - analysis Alkaline Phosphatase - metabolism Animals Animals, Newborn Calcinosis - metabolism Cell Differentiation - drug effects Cells, Cultured Collagen - analysis Collagen - biosynthesis Dose-Response Relationship, Drug estrogen receptor Histocytochemistry isoguaiacin dimethylether Lauraceae - chemistry lignans Lignans - chemistry Lignans - isolation & purification Lignans - pharmacology Machilus thunbergii Mice Mice, Inbred ICR Molecular Structure osteoblast differentiation Osteoblasts - cytology Osteoblasts - drug effects Osteoblasts - enzymology Osteoblasts - metabolism Skull - cytology
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