Revascularization for unprotected left main stem coronary artery stenosis stenting or surgery
For coronary artery disease with unprotected left main stem (LMS) stenosis, coronary artery bypass grafting (CABG) is traditionally regarded as the "standard of care" because of its well-documented and durable survival advantage. There is now an increasing trend to use drug-eluting stents...
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Veröffentlicht in: | Journal of the American College of Cardiology 2008-03, Vol.51 (9), p.885-892 |
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container_title | Journal of the American College of Cardiology |
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creator | Taggart, David P Kaul, Sanjay Boden, William E Ferguson, Jr, T Bruce Guyton, Robert A Mack, Michael J Sergeant, Paul T Shemin, Richard J Smith, Peter K Yusuf, Salim |
description | For coronary artery disease with unprotected left main stem (LMS) stenosis, coronary artery bypass grafting (CABG) is traditionally regarded as the "standard of care" because of its well-documented and durable survival advantage. There is now an increasing trend to use drug-eluting stents for LMS stenosis rather than CABG despite very little high-quality data to inform clinical practice. We herein: 1) evaluate the current evidence in support of the use of percutaneous revascularization for unprotected LMS; 2) assess the underlying justification for randomized controlled trials of stenting versus surgery for unprotected LMS; and 3) examine the optimum approach to informed consent. We conclude that CABG should indeed remain the preferred revascularization treatment in good surgical candidates with unprotected LMS stenosis. |
doi_str_mv | 10.1016/j.jacc.2007.09.067 |
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There is now an increasing trend to use drug-eluting stents for LMS stenosis rather than CABG despite very little high-quality data to inform clinical practice. We herein: 1) evaluate the current evidence in support of the use of percutaneous revascularization for unprotected LMS; 2) assess the underlying justification for randomized controlled trials of stenting versus surgery for unprotected LMS; and 3) examine the optimum approach to informed consent. We conclude that CABG should indeed remain the preferred revascularization treatment in good surgical candidates with unprotected LMS stenosis.</description><identifier>ISSN: 0735-1097</identifier><identifier>EISSN: 1558-3597</identifier><identifier>DOI: 10.1016/j.jacc.2007.09.067</identifier><identifier>PMID: 18308155</identifier><language>eng</language><publisher>United States: Elsevier Limited</publisher><subject>Cardiology ; Consent Forms ; Coronary Artery Bypass - adverse effects ; Coronary Restenosis - etiology ; Coronary Stenosis - surgery ; Coronary Stenosis - therapy ; Coronary Thrombosis - etiology ; Coronary vessels ; Drug therapy ; Drug-Eluting Stents - adverse effects ; Heart attacks ; Humans ; Mortality ; Stents ; Treatment Outcome</subject><ispartof>Journal of the American College of Cardiology, 2008-03, Vol.51 (9), p.885-892</ispartof><rights>Copyright Elsevier Limited Mar 4, 2008</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18308155$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Taggart, David P</creatorcontrib><creatorcontrib>Kaul, Sanjay</creatorcontrib><creatorcontrib>Boden, William E</creatorcontrib><creatorcontrib>Ferguson, Jr, T Bruce</creatorcontrib><creatorcontrib>Guyton, Robert A</creatorcontrib><creatorcontrib>Mack, Michael J</creatorcontrib><creatorcontrib>Sergeant, Paul T</creatorcontrib><creatorcontrib>Shemin, Richard J</creatorcontrib><creatorcontrib>Smith, Peter K</creatorcontrib><creatorcontrib>Yusuf, Salim</creatorcontrib><title>Revascularization for unprotected left main stem coronary artery stenosis stenting or surgery</title><title>Journal of the American College of Cardiology</title><addtitle>J Am Coll Cardiol</addtitle><description>For coronary artery disease with unprotected left main stem (LMS) stenosis, coronary artery bypass grafting (CABG) is traditionally regarded as the "standard of care" because of its well-documented and durable survival advantage. 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We conclude that CABG should indeed remain the preferred revascularization treatment in good surgical candidates with unprotected LMS stenosis.</description><subject>Cardiology</subject><subject>Consent Forms</subject><subject>Coronary Artery Bypass - adverse effects</subject><subject>Coronary Restenosis - etiology</subject><subject>Coronary Stenosis - surgery</subject><subject>Coronary Stenosis - therapy</subject><subject>Coronary Thrombosis - etiology</subject><subject>Coronary vessels</subject><subject>Drug therapy</subject><subject>Drug-Eluting Stents - adverse effects</subject><subject>Heart attacks</subject><subject>Humans</subject><subject>Mortality</subject><subject>Stents</subject><subject>Treatment Outcome</subject><issn>0735-1097</issn><issn>1558-3597</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkE9LxDAQxYMo7rr6BTxIQPDWOkk3TXIU8R8sCKJHKWl2ura06Zqkgn56g64XT2-Y-c3w5hFyyiBnwMrLLu-MtTkHkDnoHEq5R-ZMCJUVQst9MgdZiIyBljNyFEIHAKVi-pDMmCpAJXJOXp_wwwQ79ca3Xya2o6PN6Onktn6MaCOuaY9NpINpHQ0RB2pHPzrjP6nxEZOkphtDG36K2LoNTfth8ps0PCYHjekDnux0QV5ub56v77PV493D9dUqe-OSxUxBybFmqLjVQhgLQtdSGJRClII3VutGMbaUWquCK7FsuK6XGpmUrASOuliQi9-7yfX7hCFWQxss9r1xOE6hklAIDlIl8Pwf2I2Td8lbxQSUTMuUXKLOdtRUD7iutr4d0sfVX2zFN1QGcEU</recordid><startdate>20080304</startdate><enddate>20080304</enddate><creator>Taggart, David P</creator><creator>Kaul, Sanjay</creator><creator>Boden, William E</creator><creator>Ferguson, Jr, T Bruce</creator><creator>Guyton, Robert A</creator><creator>Mack, Michael J</creator><creator>Sergeant, Paul T</creator><creator>Shemin, Richard J</creator><creator>Smith, Peter K</creator><creator>Yusuf, Salim</creator><general>Elsevier Limited</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7T5</scope><scope>7TK</scope><scope>H94</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope></search><sort><creationdate>20080304</creationdate><title>Revascularization for unprotected left main stem coronary artery stenosis stenting or surgery</title><author>Taggart, David P ; 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source | MEDLINE; Elsevier ScienceDirect Journals; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
subjects | Cardiology Consent Forms Coronary Artery Bypass - adverse effects Coronary Restenosis - etiology Coronary Stenosis - surgery Coronary Stenosis - therapy Coronary Thrombosis - etiology Coronary vessels Drug therapy Drug-Eluting Stents - adverse effects Heart attacks Humans Mortality Stents Treatment Outcome |
title | Revascularization for unprotected left main stem coronary artery stenosis stenting or surgery |
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