Physiological Regulation and Disorders of Phosphate Metabolism -Pivotal Role of Fibroblast Growth Factor 23

Fibroblast growth factor (FGF) 23 has been identified as the last member of FGF family. FGF23 reduces serum phosphate level by suppressing proximal tubular phosphate reabsorption and intestinal phosphate absorption. FGF23 is produced by bone and acts on the kidney through a specific receptor system...

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Veröffentlicht in:	Internal Medicine 2008, Vol.47(5), pp.337-343
1. Verfasser:	Fukumoto, Seiji
Format:	Artikel
Sprache:	eng
Schlagworte:	Calcification, Physiologic - physiology Familial Hypophosphatemic Rickets - physiopathology fibroblast growth factor Fibroblast Growth Factors - physiology Glucuronidase hormone Humans hyperphosphatemia Hyperphosphatemia - physiopathology hypophosphatemia Hypophosphatemia - physiopathology Klotho Osteomalacia - physiopathology Phosphates - metabolism
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