Lytic transglycosylases: Bacterial space-making autolysins

Lytic transglycosylases are an important class of bacterial enzymes that act on peptidoglycan with the same substrate specificity as lysozyme. Unlike the latter enzymes, however, the lytic transglycosylases are not hydrolases but instead cleave the glycosidic linkage between N-actetylmuramoyl and N-...

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Veröffentlicht in:	The international journal of biochemistry & cell biology 2008, Vol.40 (4), p.586-591
Hauptverfasser:	Scheurwater, Edie, Reid, Chris W., Clarke, Anthony J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacterial cell walls Bacterial Proteins - chemistry Bacterial Proteins - genetics Bacterial Proteins - metabolism Catalytic mechanism Cell Wall - metabolism Glycosyltransferases - chemistry Glycosyltransferases - genetics Glycosyltransferases - metabolism Lytic transglycosylases Molecular Structure N-Acetylmuramoyl-L-alanine Amidase - chemistry N-Acetylmuramoyl-L-alanine Amidase - genetics N-Acetylmuramoyl-L-alanine Amidase - metabolism Peptidoglycan Peptidoglycan - metabolism
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