Central Physeal Arrests as a Manifestation of Hypervitaminosis A
Vitamin A is necessary for synthesis of visual pigments and required in appropriate amounts for membrane stability. Acute hypervitamin A intoxication can lead to increased intracranial pressure, vomiting, and lethargy. Chronic excessive intake of vitamin A can lead to pruritis, muscle and bone tende...
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| Veröffentlicht in: | Journal of pediatric orthopaedics 2007-04, Vol.27 (3), p.351-353 |
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| container_end_page | 353 |
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| container_issue | 3 |
| container_start_page | 351 |
| container_title | Journal of pediatric orthopaedics |
| container_volume | 27 |
| creator | Saltzman, Matthew D King, Erik C |
| description | Vitamin A is necessary for synthesis of visual pigments and required in appropriate amounts for membrane stability. Acute hypervitamin A intoxication can lead to increased intracranial pressure, vomiting, and lethargy. Chronic excessive intake of vitamin A can lead to pruritis, muscle and bone tenderness, and failure to thrive. Reported effects of hypervitamin A intoxication on bone include osteoporosis, fracture, cortical thickening, and metaphyseal irregularity. We are reporting on a case of central physeal arrest in the distal femur, proximal tibia, and distal tibia after excessive intake of vitamin A. |
| doi_str_mv | 10.1097/BPO.0b013e3180340a06 |
| format | Article |
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Acute hypervitamin A intoxication can lead to increased intracranial pressure, vomiting, and lethargy. Chronic excessive intake of vitamin A can lead to pruritis, muscle and bone tenderness, and failure to thrive. Reported effects of hypervitamin A intoxication on bone include osteoporosis, fracture, cortical thickening, and metaphyseal irregularity. We are reporting on a case of central physeal arrest in the distal femur, proximal tibia, and distal tibia after excessive intake of vitamin A.</description><identifier>ISSN: 0271-6798</identifier><identifier>EISSN: 1539-2570</identifier><identifier>DOI: 10.1097/BPO.0b013e3180340a06</identifier><identifier>PMID: 17414024</identifier><identifier>CODEN: JPORDO</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott Williams & Wilkins, Inc</publisher><subject>Biological and medical sciences ; Child, Preschool ; Diseases of the osteoarticular system ; Epiphyses - diagnostic imaging ; Epiphyses - drug effects ; Femur - diagnostic imaging ; Femur - drug effects ; Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy ; Humans ; Hypervitaminosis A - complications ; Hypervitaminosis A - diagnostic imaging ; Injuries of the limb. Injuries of the spine ; Male ; Medical sciences ; Nervous system (semeiology, syndromes) ; Neurology ; Osteoporosis. Osteomalacia. Paget disease ; Radiography ; Tibia - diagnostic imaging ; Tibia - drug effects ; Traumas. 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Acute hypervitamin A intoxication can lead to increased intracranial pressure, vomiting, and lethargy. Chronic excessive intake of vitamin A can lead to pruritis, muscle and bone tenderness, and failure to thrive. Reported effects of hypervitamin A intoxication on bone include osteoporosis, fracture, cortical thickening, and metaphyseal irregularity. We are reporting on a case of central physeal arrest in the distal femur, proximal tibia, and distal tibia after excessive intake of vitamin A.</description><subject>Biological and medical sciences</subject><subject>Child, Preschool</subject><subject>Diseases of the osteoarticular system</subject><subject>Epiphyses - diagnostic imaging</subject><subject>Epiphyses - drug effects</subject><subject>Femur - diagnostic imaging</subject><subject>Femur - drug effects</subject><subject>Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy</subject><subject>Humans</subject><subject>Hypervitaminosis A - complications</subject><subject>Hypervitaminosis A - diagnostic imaging</subject><subject>Injuries of the limb. Injuries of the spine</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Nervous system (semeiology, syndromes)</subject><subject>Neurology</subject><subject>Osteoporosis. Osteomalacia. Paget disease</subject><subject>Radiography</subject><subject>Tibia - diagnostic imaging</subject><subject>Tibia - drug effects</subject><subject>Traumas. Diseases due to physical agents</subject><issn>0271-6798</issn><issn>1539-2570</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkF1LwzAUhoMobk7_gUhv9K7z5KNNcucc6oTJdqHXIe0SFu3ambSO_XszLAyEhEPCc07ePAhdYxhjkPz-cbkYQwGYGooFUAYa8hM0xBmVKck4nKIhEI7TnEsxQBchfAJgThk9RwPMGWZA2BA9TE3del0ly_U-mFgn3pvQhkTHlbzp2tl41K1r6qSxyWy_Nf7HtXrj6ia4kEwu0ZnVVTBXfR2hj-en9-ksnS9eXqeTeVpSAZAWlgtGBS0ME7IsJV2tNGdQWBuvc8pzyU1utTSljr8hhEuI-TIhoMiw5JqO0N3f3K1vvruYSW1cKE1V6do0XVA8KuAkIxFkf2DpmxC8sWrr3Ub7vcKgDuZUNKf-m4ttN_38rtiY1bGpVxWB2x7QodSV9bouXThyImeH0Mf3d03VGh--qm5nvFpHue1aASYMUylSAsCBQVQTNwH6Cyc6hPc</recordid><startdate>200704</startdate><enddate>200704</enddate><creator>Saltzman, Matthew D</creator><creator>King, Erik C</creator><general>Lippincott Williams & Wilkins, Inc</general><general>Lippincott</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200704</creationdate><title>Central Physeal Arrests as a Manifestation of Hypervitaminosis A</title><author>Saltzman, Matthew D ; King, Erik C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3800-bf784383be489cc93dda740bff843637697e6fa9eca180227900245880b5197a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Biological and medical sciences</topic><topic>Child, Preschool</topic><topic>Diseases of the osteoarticular system</topic><topic>Epiphyses - diagnostic imaging</topic><topic>Epiphyses - drug effects</topic><topic>Femur - diagnostic imaging</topic><topic>Femur - drug effects</topic><topic>Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy</topic><topic>Humans</topic><topic>Hypervitaminosis A - complications</topic><topic>Hypervitaminosis A - diagnostic imaging</topic><topic>Injuries of the limb. Injuries of the spine</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Nervous system (semeiology, syndromes)</topic><topic>Neurology</topic><topic>Osteoporosis. Osteomalacia. Paget disease</topic><topic>Radiography</topic><topic>Tibia - diagnostic imaging</topic><topic>Tibia - drug effects</topic><topic>Traumas. Diseases due to physical agents</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Saltzman, Matthew D</creatorcontrib><creatorcontrib>King, Erik C</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of pediatric orthopaedics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Saltzman, Matthew D</au><au>King, Erik C</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Central Physeal Arrests as a Manifestation of Hypervitaminosis A</atitle><jtitle>Journal of pediatric orthopaedics</jtitle><addtitle>J Pediatr Orthop</addtitle><date>2007-04</date><risdate>2007</risdate><volume>27</volume><issue>3</issue><spage>351</spage><epage>353</epage><pages>351-353</pages><issn>0271-6798</issn><eissn>1539-2570</eissn><coden>JPORDO</coden><abstract>Vitamin A is necessary for synthesis of visual pigments and required in appropriate amounts for membrane stability. Acute hypervitamin A intoxication can lead to increased intracranial pressure, vomiting, and lethargy. Chronic excessive intake of vitamin A can lead to pruritis, muscle and bone tenderness, and failure to thrive. Reported effects of hypervitamin A intoxication on bone include osteoporosis, fracture, cortical thickening, and metaphyseal irregularity. We are reporting on a case of central physeal arrest in the distal femur, proximal tibia, and distal tibia after excessive intake of vitamin A.</abstract><cop>Hagerstown, MD</cop><pub>Lippincott Williams & Wilkins, Inc</pub><pmid>17414024</pmid><doi>10.1097/BPO.0b013e3180340a06</doi><tpages>3</tpages></addata></record> |
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| ispartof | Journal of pediatric orthopaedics, 2007-04, Vol.27 (3), p.351-353 |
| issn | 0271-6798 1539-2570 |
| language | eng |
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| source | MEDLINE; Journals@Ovid Complete |
| subjects | Biological and medical sciences Child, Preschool Diseases of the osteoarticular system Epiphyses - diagnostic imaging Epiphyses - drug effects Femur - diagnostic imaging Femur - drug effects Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy Humans Hypervitaminosis A - complications Hypervitaminosis A - diagnostic imaging Injuries of the limb. Injuries of the spine Male Medical sciences Nervous system (semeiology, syndromes) Neurology Osteoporosis. Osteomalacia. Paget disease Radiography Tibia - diagnostic imaging Tibia - drug effects Traumas. Diseases due to physical agents |
| title | Central Physeal Arrests as a Manifestation of Hypervitaminosis A |
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