Prediction of protein functional residues from sequence by probability density estimation

Motivation: The prediction of ligand-binding residues or catalytically active residues of a protein may give important hints that can guide further genetic or biochemical studies. Existing sequence-based prediction methods mostly rank residue positions by evolutionary conservation calculated from a...

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Veröffentlicht in:	Bioinformatics 2008-03, Vol.24 (5), p.613-620
Hauptverfasser:	Fischer, J. D., Mayer, C. E., Söding, J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Catalytic Domain Fundamental and applied biological sciences. Psychology General aspects Mathematics in biology. Statistical analysis. Models. Metrology. Data processing in biology (general aspects) Probability Proteins - chemistry Proteins - physiology
Online-Zugang:	Volltext
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