A Concise Synthesis of the Naphthalene Portion of Purpuromycin

A concise synthesis of naphthalene compounds for incorporation into a synthetic sequence for the rubromycin family of natural products is presented. These highly substituted naphthalenes are generated in seven and nine steps, respectively, from 2,4,5-trimethoxybenzaldehyde. Three ring-forming method...

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Veröffentlicht in:	Journal of organic chemistry 2008-03, Vol.73 (5), p.1911-1918
Hauptverfasser:	Lowell, Andrew N, Fennie, Michael W, Kozlowski, Marisa C
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemistry Condensed benzenic and aromatic compounds Exact sciences and technology Magnetic Resonance Spectroscopy Naphthalenes - chemistry Naphthoquinones - chemical synthesis Naphthoquinones - chemistry Organic chemistry Preparations and properties Spectrometry, Mass, Electrospray Ionization Spectrophotometry, Infrared
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