Confirmation of the Stereostructure of (+)-Cytostatin by Fluorous Mixture Synthesis of Four Candidate Stereoisomers

Mix and match: Four closely related candidate isomers for cytostatin have been synthesized by using the technique of fluorous mixture synthesis. Comparison of NMR, thin‐layer chromatography, and optical rotation data enabled the three isomers that were not cytostatin to be identified. Thus, by a pro...

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Veröffentlicht in:	Angewandte Chemie (International ed.) 2008-01, Vol.47 (6), p.1130-1133
Hauptverfasser:	Jung, Won-Hyuk, Guyenne, Sabrina, Riesco-Fagundo, Concepción, Mancuso, John, Nakamura, Shuichi, Curran, Dennis P
Format:	Artikel
Sprache:	eng
Schlagworte:	antitumor agents cytostatin Fluorine Compounds - chemistry fluorous tags Molecular Structure natural products Organophosphates - chemical synthesis Organophosphates - chemistry Pyrones - chemical synthesis Pyrones - chemistry Stereoisomerism structure elucidation
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