Primary epithelioid hemangioendothelioma of the lumbar spine
Abstract Background context Primary epitheliod hemangioendotheliomas of the lumbar spine are extremely rare tumors with an unpredictable clinical course. Purpose To present a case of primary lumbar epithelioid hemangioendothelioma and its treatment protocol. Study design/setting A tertiary Spinal Un...
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Veröffentlicht in: | The spine journal 2008-03, Vol.8 (2), p.385-390 |
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creator | Christodoulou, Anastasios, MD, PhD Symeonidis, Panagiotis D., MD Kapoutsis, Dimitrios, MD Iordanidis, Fotis, MD |
description | Abstract Background context Primary epitheliod hemangioendotheliomas of the lumbar spine are extremely rare tumors with an unpredictable clinical course. Purpose To present a case of primary lumbar epithelioid hemangioendothelioma and its treatment protocol. Study design/setting A tertiary Spinal Unit. Patient sample A previously healthy adult with persisting low back pain and neurologic deficit. Methods The diagnosis was confirmed by core needle biopsy. The patient was treated with preoperative embolization followed by staged surgery which included wide tumor resection and spinal fixation, using a cage system and a titanium plate anteriorly and a transpedicular fixation system posteriorly. Results Three years postoperatively the patient remains free of symptoms with no evidence of recurrence. Conclusions The treatment of these unpredictable tumors should be dictated by adherence to general oncologic principles. |
doi_str_mv | 10.1016/j.spinee.2006.10.016 |
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Purpose To present a case of primary lumbar epithelioid hemangioendothelioma and its treatment protocol. Study design/setting A tertiary Spinal Unit. Patient sample A previously healthy adult with persisting low back pain and neurologic deficit. Methods The diagnosis was confirmed by core needle biopsy. The patient was treated with preoperative embolization followed by staged surgery which included wide tumor resection and spinal fixation, using a cage system and a titanium plate anteriorly and a transpedicular fixation system posteriorly. Results Three years postoperatively the patient remains free of symptoms with no evidence of recurrence. Conclusions The treatment of these unpredictable tumors should be dictated by adherence to general oncologic principles.</description><identifier>ISSN: 1529-9430</identifier><identifier>EISSN: 1878-1632</identifier><identifier>DOI: 10.1016/j.spinee.2006.10.016</identifier><identifier>PMID: 18299105</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Adult ; Back Pain - etiology ; Embolization ; Epithelioid hemangioendothelioma ; Hemangioendothelioma, Epithelioid - complications ; Hemangioendothelioma, Epithelioid - pathology ; Hemangioendothelioma, Epithelioid - surgery ; Hemicorpectomy ; Humans ; Internal Fixators ; Lumbar Vertebrae ; Magnetic Resonance Imaging ; Male ; Orthopedics ; Reconstructive Surgical Procedures ; Spinal Neoplasms - complications ; Spinal Neoplasms - pathology ; Spinal Neoplasms - surgery ; Titanium cage ; Tomography, X-Ray Computed ; Vascular tumours</subject><ispartof>The spine journal, 2008-03, Vol.8 (2), p.385-390</ispartof><rights>Elsevier Inc.</rights><rights>2008 Elsevier Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c415t-31918a502a5407b841a595e569b5ae7290bf4117e2d67d408678440248fb8d483</citedby><cites>FETCH-LOGICAL-c415t-31918a502a5407b841a595e569b5ae7290bf4117e2d67d408678440248fb8d483</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S1529943006010151$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18299105$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Christodoulou, Anastasios, MD, PhD</creatorcontrib><creatorcontrib>Symeonidis, Panagiotis D., MD</creatorcontrib><creatorcontrib>Kapoutsis, Dimitrios, MD</creatorcontrib><creatorcontrib>Iordanidis, Fotis, MD</creatorcontrib><title>Primary epithelioid hemangioendothelioma of the lumbar spine</title><title>The spine journal</title><addtitle>Spine J</addtitle><description>Abstract Background context Primary epitheliod hemangioendotheliomas of the lumbar spine are extremely rare tumors with an unpredictable clinical course. Purpose To present a case of primary lumbar epithelioid hemangioendothelioma and its treatment protocol. Study design/setting A tertiary Spinal Unit. Patient sample A previously healthy adult with persisting low back pain and neurologic deficit. Methods The diagnosis was confirmed by core needle biopsy. The patient was treated with preoperative embolization followed by staged surgery which included wide tumor resection and spinal fixation, using a cage system and a titanium plate anteriorly and a transpedicular fixation system posteriorly. Results Three years postoperatively the patient remains free of symptoms with no evidence of recurrence. Conclusions The treatment of these unpredictable tumors should be dictated by adherence to general oncologic principles.</description><subject>Adult</subject><subject>Back Pain - etiology</subject><subject>Embolization</subject><subject>Epithelioid hemangioendothelioma</subject><subject>Hemangioendothelioma, Epithelioid - complications</subject><subject>Hemangioendothelioma, Epithelioid - pathology</subject><subject>Hemangioendothelioma, Epithelioid - surgery</subject><subject>Hemicorpectomy</subject><subject>Humans</subject><subject>Internal Fixators</subject><subject>Lumbar Vertebrae</subject><subject>Magnetic Resonance Imaging</subject><subject>Male</subject><subject>Orthopedics</subject><subject>Reconstructive Surgical Procedures</subject><subject>Spinal Neoplasms - complications</subject><subject>Spinal Neoplasms - pathology</subject><subject>Spinal Neoplasms - surgery</subject><subject>Titanium cage</subject><subject>Tomography, X-Ray Computed</subject><subject>Vascular tumours</subject><issn>1529-9430</issn><issn>1878-1632</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkUFL7TAQhYMo6lP_gUhX7nqdSZM2BRFE9D1BUFDXIW2nmmvbXJNbwX9v-npBcONqho8zZ5gzjB0jLBAwP1suwsoORAsOkEe0iHCL7aMqVIp5xrdjL3mZliKDPfYnhCUAqAL5LttDxcsSQe6z8wdve-M_E1rZ9St11tkmeaXeDC_W0dC4GfYmcW0S-6Qb-8r45P_uQ7bTmi7Q0aYesOeb66erf-nd_d_bq8u7tBYo12mGJSojgRspoKiUQCNLSTIvK2mo4CVUrUAsiDd50QhQeaGEAC5UW6lGqOyAnc6-K-_eRwpr3dtQU9eZgdwYdAGZiC5ZFIpZWHsXgqdWr-bzNIKeUtNLPaemp9QmGmEcO9n4j1VPzffQJqYouJgFFK_8sOR1qC0NNTXWU73WjbO_bfhpUHd2sLXp3uiTwtKNfogJatSBa9CP0-emx0EO0VRi9gXIC5Mb</recordid><startdate>20080301</startdate><enddate>20080301</enddate><creator>Christodoulou, Anastasios, MD, PhD</creator><creator>Symeonidis, Panagiotis D., MD</creator><creator>Kapoutsis, Dimitrios, MD</creator><creator>Iordanidis, Fotis, MD</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20080301</creationdate><title>Primary epithelioid hemangioendothelioma of the lumbar spine</title><author>Christodoulou, Anastasios, MD, PhD ; Symeonidis, Panagiotis D., MD ; Kapoutsis, Dimitrios, MD ; Iordanidis, Fotis, MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c415t-31918a502a5407b841a595e569b5ae7290bf4117e2d67d408678440248fb8d483</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Adult</topic><topic>Back Pain - etiology</topic><topic>Embolization</topic><topic>Epithelioid hemangioendothelioma</topic><topic>Hemangioendothelioma, Epithelioid - complications</topic><topic>Hemangioendothelioma, Epithelioid - pathology</topic><topic>Hemangioendothelioma, Epithelioid - surgery</topic><topic>Hemicorpectomy</topic><topic>Humans</topic><topic>Internal Fixators</topic><topic>Lumbar Vertebrae</topic><topic>Magnetic Resonance Imaging</topic><topic>Male</topic><topic>Orthopedics</topic><topic>Reconstructive Surgical Procedures</topic><topic>Spinal Neoplasms - complications</topic><topic>Spinal Neoplasms - pathology</topic><topic>Spinal Neoplasms - surgery</topic><topic>Titanium cage</topic><topic>Tomography, X-Ray Computed</topic><topic>Vascular tumours</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Christodoulou, Anastasios, MD, PhD</creatorcontrib><creatorcontrib>Symeonidis, Panagiotis D., MD</creatorcontrib><creatorcontrib>Kapoutsis, Dimitrios, MD</creatorcontrib><creatorcontrib>Iordanidis, Fotis, MD</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The spine journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Christodoulou, Anastasios, MD, PhD</au><au>Symeonidis, Panagiotis D., MD</au><au>Kapoutsis, Dimitrios, MD</au><au>Iordanidis, Fotis, MD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Primary epithelioid hemangioendothelioma of the lumbar spine</atitle><jtitle>The spine journal</jtitle><addtitle>Spine J</addtitle><date>2008-03-01</date><risdate>2008</risdate><volume>8</volume><issue>2</issue><spage>385</spage><epage>390</epage><pages>385-390</pages><issn>1529-9430</issn><eissn>1878-1632</eissn><abstract>Abstract Background context Primary epitheliod hemangioendotheliomas of the lumbar spine are extremely rare tumors with an unpredictable clinical course. Purpose To present a case of primary lumbar epithelioid hemangioendothelioma and its treatment protocol. Study design/setting A tertiary Spinal Unit. Patient sample A previously healthy adult with persisting low back pain and neurologic deficit. Methods The diagnosis was confirmed by core needle biopsy. The patient was treated with preoperative embolization followed by staged surgery which included wide tumor resection and spinal fixation, using a cage system and a titanium plate anteriorly and a transpedicular fixation system posteriorly. Results Three years postoperatively the patient remains free of symptoms with no evidence of recurrence. Conclusions The treatment of these unpredictable tumors should be dictated by adherence to general oncologic principles.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>18299105</pmid><doi>10.1016/j.spinee.2006.10.016</doi><tpages>6</tpages></addata></record> |
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subjects | Adult Back Pain - etiology Embolization Epithelioid hemangioendothelioma Hemangioendothelioma, Epithelioid - complications Hemangioendothelioma, Epithelioid - pathology Hemangioendothelioma, Epithelioid - surgery Hemicorpectomy Humans Internal Fixators Lumbar Vertebrae Magnetic Resonance Imaging Male Orthopedics Reconstructive Surgical Procedures Spinal Neoplasms - complications Spinal Neoplasms - pathology Spinal Neoplasms - surgery Titanium cage Tomography, X-Ray Computed Vascular tumours |
title | Primary epithelioid hemangioendothelioma of the lumbar spine |
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