Comparison of two indirect techniques for local delivery of a high dose of an antimicrobial in the distal portion of forelimbs of horses

To compare isolated limb retrograde venous injection (ILRVI) and isolated limb infusion (ILI) for delivery of amikacin to the synovial fluid of the distal interphalangeal and metacarpophalangeal joints and to evaluate the efficacy of use of an Esmarch tourniquet in standing horses. 6 healthy adult h...

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Veröffentlicht in:	American journal of veterinary research 2008-03, Vol.69 (3), p.334-342
Hauptverfasser:	Errico, J.A, Trumble, T.N, Bueno, A.C.D, Davis, J.L, Brown, M.P
Format:	Artikel
Sprache:	eng
Schlagworte:	amikacin Amikacin - administration & dosage Amikacin - blood Amikacin - pharmacokinetics Animals Anti-Infective Agents - administration & dosage Anti-Infective Agents - blood Anti-Infective Agents - pharmacokinetics antimicrobial agents Cross-Over Studies dosage drug injection Esmarch tourniquet Female Forelimb - metabolism forelimbs horses Horses - blood Horses - metabolism Infusions, Intraosseous - veterinary Injections, Intravenous - veterinary isolated limb infusion isolated limb retrograde venous injection joints (animal) new methods Perfusion - veterinary synovial fluid Synovial Fluid - metabolism Tourniquets - veterinary veterinary equipment
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