An Elderly Case of Type 2 Diabetes which Developed in Association with Oral and Esophageal Candidiasis
A 75-year-old woman who had been healthy except for mild glycemia and lipidemia discovered three and a half months before admission experienced severe dysphagia secondary to oral and esophageal candidiasis. She eventually developed diabetic hyperosmolar syndrome and ketoacidosis. Since anti-GAD anti...
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| Veröffentlicht in: | Internal Medicine 2007, Vol.46(7), pp.387-390 |
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| container_title | Internal Medicine |
| container_volume | 46 |
| creator | Takasawa, Hirofumi Takahashi, Yoshihiko Abe, Makiko Osame, Keiichiro Watanabe, Shigeru Hisatake, Tomoko Yasuda, Kazuki Kaburagi, Yasushi Kajio, Hiroshi Noda, Mitsuhiko |
| description | A 75-year-old woman who had been healthy except for mild glycemia and lipidemia discovered three and a half months before admission experienced severe dysphagia secondary to oral and esophageal candidiasis. She eventually developed diabetic hyperosmolar syndrome and ketoacidosis. Since anti-GAD antibody was negative and her diabetes was controlled with a moderate dose of insulin, we made a diagnosis of type 2 diabetes. Her only risk factors for candidiasis were hyperglycemia, age, and continuous denture use. The fact that her diabetes developed in association with oral candidiasis supports the hypothesis that there is a bidirectional interrelationship between diabetes and oral infection. |
| doi_str_mv | 10.2169/internalmedicine.46.1898 |
| format | Article |
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She eventually developed diabetic hyperosmolar syndrome and ketoacidosis. Since anti-GAD antibody was negative and her diabetes was controlled with a moderate dose of insulin, we made a diagnosis of type 2 diabetes. Her only risk factors for candidiasis were hyperglycemia, age, and continuous denture use. The fact that her diabetes developed in association with oral candidiasis supports the hypothesis that there is a bidirectional interrelationship between diabetes and oral infection.</description><identifier>ISSN: 0918-2918</identifier><identifier>EISSN: 1349-7235</identifier><identifier>DOI: 10.2169/internalmedicine.46.1898</identifier><identifier>PMID: 17409603</identifier><language>eng</language><publisher>Japan: The Japanese Society of Internal Medicine</publisher><subject>Aged ; Antifungal Agents - therapeutic use ; candidiasis ; Candidiasis, Oral - complications ; Candidiasis, Oral - diagnosis ; Candidiasis, Oral - drug therapy ; denture ; Diabetes Mellitus, Type 2 - complications ; Diabetes Mellitus, Type 2 - diagnosis ; Diabetes Mellitus, Type 2 - drug therapy ; Esophageal Diseases - complications ; Esophageal Diseases - drug therapy ; Esophageal Diseases - microbiology ; Female ; Follow-Up Studies ; Humans ; hyperosmolar syndrome ; Hypoglycemic Agents - therapeutic use ; ketoacidosis ; Risk Assessment ; Severity of Illness Index</subject><ispartof>Internal Medicine, 2007, Vol.46(7), pp.387-390</ispartof><rights>2007 by The Japanese Society of Internal Medicine</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c522t-6fc452a278235782566bfa08e75562a2e871ca5d583158879512c0efd872323c3</citedby><cites>FETCH-LOGICAL-c522t-6fc452a278235782566bfa08e75562a2e871ca5d583158879512c0efd872323c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,1882,27923,27924</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17409603$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Takasawa, Hirofumi</creatorcontrib><creatorcontrib>Takahashi, Yoshihiko</creatorcontrib><creatorcontrib>Abe, Makiko</creatorcontrib><creatorcontrib>Osame, Keiichiro</creatorcontrib><creatorcontrib>Watanabe, Shigeru</creatorcontrib><creatorcontrib>Hisatake, Tomoko</creatorcontrib><creatorcontrib>Yasuda, Kazuki</creatorcontrib><creatorcontrib>Kaburagi, Yasushi</creatorcontrib><creatorcontrib>Kajio, Hiroshi</creatorcontrib><creatorcontrib>Noda, Mitsuhiko</creatorcontrib><title>An Elderly Case of Type 2 Diabetes which Developed in Association with Oral and Esophageal Candidiasis</title><title>Internal Medicine</title><addtitle>Intern. Med.</addtitle><description>A 75-year-old woman who had been healthy except for mild glycemia and lipidemia discovered three and a half months before admission experienced severe dysphagia secondary to oral and esophageal candidiasis. She eventually developed diabetic hyperosmolar syndrome and ketoacidosis. Since anti-GAD antibody was negative and her diabetes was controlled with a moderate dose of insulin, we made a diagnosis of type 2 diabetes. Her only risk factors for candidiasis were hyperglycemia, age, and continuous denture use. The fact that her diabetes developed in association with oral candidiasis supports the hypothesis that there is a bidirectional interrelationship between diabetes and oral infection.</description><subject>Aged</subject><subject>Antifungal Agents - therapeutic use</subject><subject>candidiasis</subject><subject>Candidiasis, Oral - complications</subject><subject>Candidiasis, Oral - diagnosis</subject><subject>Candidiasis, Oral - drug therapy</subject><subject>denture</subject><subject>Diabetes Mellitus, Type 2 - complications</subject><subject>Diabetes Mellitus, Type 2 - diagnosis</subject><subject>Diabetes Mellitus, Type 2 - drug therapy</subject><subject>Esophageal Diseases - complications</subject><subject>Esophageal Diseases - drug therapy</subject><subject>Esophageal Diseases - microbiology</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>hyperosmolar syndrome</subject><subject>Hypoglycemic Agents - therapeutic use</subject><subject>ketoacidosis</subject><subject>Risk Assessment</subject><subject>Severity of Illness Index</subject><issn>0918-2918</issn><issn>1349-7235</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkctOwzAQRS0EgvL4BeQVuxQ_4sRZVm15SJW6KWvLdSbEyHWCnVL173HVCiTE5lpjn5nRvUYIUzJmtKgerR8geO02UFtjPYzzYkxlJc_QiPK8ykrGxTkakYrKjCW5QtcxfhDCZVmxS3RFy5xUBeEj1Ew8nrsagtvjqY6Auwav9j1ghmdWr2GAiHetNS2ewRe4rocaW48nMXbG6sF2Hu_s0OJl0A5rX-N57PpWv0Mqp6m2tdXRxlt00WgX4e503qC3p_lq-pItls-v08kiM4KxISsakwumWSmTgSSiKNaNJhJKIYp0D7KkRotaSE6FTGYEZYZAU8vkmHHDb9DDcW4fus8txEFtbDTgnPbQbaMqCeeHvgTKI2hCF2OARvXBbnTYK0rUIWP1N2OVF-qQcWq9P-3YrtPjb-Mp1AQsjsBHHFISP4AOgzUO_p1cHiV90A9mWh0UeP4NQ36Y2Q</recordid><startdate>20070101</startdate><enddate>20070101</enddate><creator>Takasawa, Hirofumi</creator><creator>Takahashi, Yoshihiko</creator><creator>Abe, Makiko</creator><creator>Osame, Keiichiro</creator><creator>Watanabe, Shigeru</creator><creator>Hisatake, Tomoko</creator><creator>Yasuda, Kazuki</creator><creator>Kaburagi, Yasushi</creator><creator>Kajio, Hiroshi</creator><creator>Noda, Mitsuhiko</creator><general>The Japanese Society of Internal Medicine</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20070101</creationdate><title>An Elderly Case of Type 2 Diabetes which Developed in Association with Oral and Esophageal Candidiasis</title><author>Takasawa, Hirofumi ; Takahashi, Yoshihiko ; Abe, Makiko ; Osame, Keiichiro ; Watanabe, Shigeru ; Hisatake, Tomoko ; Yasuda, Kazuki ; Kaburagi, Yasushi ; Kajio, Hiroshi ; Noda, Mitsuhiko</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c522t-6fc452a278235782566bfa08e75562a2e871ca5d583158879512c0efd872323c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Aged</topic><topic>Antifungal Agents - therapeutic use</topic><topic>candidiasis</topic><topic>Candidiasis, Oral - complications</topic><topic>Candidiasis, Oral - diagnosis</topic><topic>Candidiasis, Oral - drug therapy</topic><topic>denture</topic><topic>Diabetes Mellitus, Type 2 - complications</topic><topic>Diabetes Mellitus, Type 2 - diagnosis</topic><topic>Diabetes Mellitus, Type 2 - drug therapy</topic><topic>Esophageal Diseases - complications</topic><topic>Esophageal Diseases - drug therapy</topic><topic>Esophageal Diseases - microbiology</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>hyperosmolar syndrome</topic><topic>Hypoglycemic Agents - therapeutic use</topic><topic>ketoacidosis</topic><topic>Risk Assessment</topic><topic>Severity of Illness Index</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Takasawa, Hirofumi</creatorcontrib><creatorcontrib>Takahashi, Yoshihiko</creatorcontrib><creatorcontrib>Abe, Makiko</creatorcontrib><creatorcontrib>Osame, Keiichiro</creatorcontrib><creatorcontrib>Watanabe, Shigeru</creatorcontrib><creatorcontrib>Hisatake, Tomoko</creatorcontrib><creatorcontrib>Yasuda, Kazuki</creatorcontrib><creatorcontrib>Kaburagi, Yasushi</creatorcontrib><creatorcontrib>Kajio, Hiroshi</creatorcontrib><creatorcontrib>Noda, Mitsuhiko</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Internal Medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Takasawa, Hirofumi</au><au>Takahashi, Yoshihiko</au><au>Abe, Makiko</au><au>Osame, Keiichiro</au><au>Watanabe, Shigeru</au><au>Hisatake, Tomoko</au><au>Yasuda, Kazuki</au><au>Kaburagi, Yasushi</au><au>Kajio, Hiroshi</au><au>Noda, Mitsuhiko</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>An Elderly Case of Type 2 Diabetes which Developed in Association with Oral and Esophageal Candidiasis</atitle><jtitle>Internal Medicine</jtitle><addtitle>Intern. Med.</addtitle><date>2007-01-01</date><risdate>2007</risdate><volume>46</volume><issue>7</issue><spage>387</spage><epage>390</epage><pages>387-390</pages><issn>0918-2918</issn><eissn>1349-7235</eissn><abstract>A 75-year-old woman who had been healthy except for mild glycemia and lipidemia discovered three and a half months before admission experienced severe dysphagia secondary to oral and esophageal candidiasis. She eventually developed diabetic hyperosmolar syndrome and ketoacidosis. Since anti-GAD antibody was negative and her diabetes was controlled with a moderate dose of insulin, we made a diagnosis of type 2 diabetes. Her only risk factors for candidiasis were hyperglycemia, age, and continuous denture use. The fact that her diabetes developed in association with oral candidiasis supports the hypothesis that there is a bidirectional interrelationship between diabetes and oral infection.</abstract><cop>Japan</cop><pub>The Japanese Society of Internal Medicine</pub><pmid>17409603</pmid><doi>10.2169/internalmedicine.46.1898</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Aged Antifungal Agents - therapeutic use candidiasis Candidiasis, Oral - complications Candidiasis, Oral - diagnosis Candidiasis, Oral - drug therapy denture Diabetes Mellitus, Type 2 - complications Diabetes Mellitus, Type 2 - diagnosis Diabetes Mellitus, Type 2 - drug therapy Esophageal Diseases - complications Esophageal Diseases - drug therapy Esophageal Diseases - microbiology Female Follow-Up Studies Humans hyperosmolar syndrome Hypoglycemic Agents - therapeutic use ketoacidosis Risk Assessment Severity of Illness Index |
| title | An Elderly Case of Type 2 Diabetes which Developed in Association with Oral and Esophageal Candidiasis |
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