MyD88-Dependent Activation of B220-CD11b+LY-6C+ Dendritic Cells during Brucella melitensis Infection

IFN-gamma is a key cytokine controlling Brucella infection. One of its major function is the stimulation of Brucella-killing effector mechanisms, such as inducible NO synthase (iNOS)/NOS2 activity, in phagocytic cells. In this study, an attempt to identify the main cellular components of the immune...

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Veröffentlicht in:	The Journal of immunology (1950) 2007-04, Vol.178 (8), p.5182-5191
Hauptverfasser:	Copin, Richard, De Baetselier, Patrick, Carlier, Yves, Letesson, Jean-Jacques, Muraille, Eric
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens, Ly - physiology Brucella melitensis Brucellosis - immunology CD11b Antigen - physiology CD4-Positive T-Lymphocytes - immunology Dendritic Cells - physiology Female Interferon-gamma - physiology Leukocyte Common Antigens - physiology Mice Mice, Inbred BALB C Mice, Inbred C57BL Myeloid Differentiation Factor 88 - physiology Nitric Oxide Synthase Type II - physiology Toll-Like Receptor 4 - physiology Toll-Like Receptor 9 - physiology
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