A hydrophobic loop in acyl-CoA binding protein is functionally important for binding to palmitoyl-coenzyme A: A molecular dynamics study

Acyl-CoA binding protein (ACBP) plays a key role in lipid metabolism, interacting via a partly unknown mechanism with high affinity with long chain fatty acyl-CoAs (LCFA-CoAs). At present there is no study of the microscopic way ligand binding is accomplished. We analyzed this process by molecular d...

Ausführliche Beschreibung