Critical Synergy of CD30 and OX40 Signals in CD4 T Cell Homeostasis and Th1 Immunity to Salmonella

CD30 and OX40 (CD134) are members of the TNFR superfamily expressed on activated CD4 T cells, and mice deficient in both these molecules harbor a striking defect in the capacity to mount CD4 T cell-dependent memory Ab responses. This article shows that these mice also fail to control Salmonella infe...

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Veröffentlicht in:The Journal of immunology (1950) 2008-03, Vol.180 (5), p.2824-2829
Hauptverfasser: Gaspal, Fabrina, Bekiaris, Vasileios, Kim, Mi-Yeon, Withers, David R, Bobat, Saeeda, MacLennan, Ian C. M, Anderson, Graham, Lane, Peter J, Cunningham, Adam F
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Sprache:eng
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