Association study of serotonin 2A receptor (5-HT2A) and serotonin transporter (5-HTT) gene polymorphisms with schizophrenia

To investigate (i) the association between four serotonergic polymorphisms (A-1438G and T102C of the 5-HT2A receptor gene, and 5-HTT VNTR and 5-HTTLPR of the 5-HT transporter gene) and schizophrenia and (ii) the potential interaction of those polymorphisms in the development of schizophrenia. 227 ou...

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Veröffentlicht in:	Progress in neuro-psychopharmacology & biological psychiatry 2007-04, Vol.31 (3), p.741-745
Hauptverfasser:	Sáiz, Pilar A., García-Portilla, M. Paz, Arango, Celso, Morales, Blanca, Alvarez, Victoria, Coto, Eliécer, Fernández, Juan M., Bascarán, M. Teresa, Bousoño, Manuel, Bobes, Julio
Format:	Artikel
Sprache:	eng
Schlagworte:	5-HT2A polymorphisms 5-HTT polymorphisms Adult Adult and adolescent clinical studies Alleles Biological and medical sciences Chi-Square Distribution Female Gene Frequency Genetic association Genetic Predisposition to Disease Humans Linkage Disequilibrium Male Medical sciences Middle Aged Neuropharmacology Pharmacology. Drug treatments Polymorphism, Genetic Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Psychoses Receptor, Serotonin, 5-HT2A - genetics Schizophrenia Schizophrenia - genetics Serotonin Plasma Membrane Transport Proteins - genetics Spain
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