Association between the MnSOD Ala-9Val polymorphism and development of schizophrenia and abnormal involuntary movements in the Xhosa population

Reactive oxygen species (ROS)-mediated damage has been hypothesized to play a role in the development and poor outcome of schizophrenia, as well as the development of neuroleptic-induced abnormal involuntary movements. Recently, the functional polymorphism (Ala-9Val) in the manganese superoxide dism...

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Veröffentlicht in:	Progress in neuro-psychopharmacology & biological psychiatry 2007-04, Vol.31 (3), p.664-672
Hauptverfasser:	Hitzeroth, Angelika, Niehaus, Dana J.H., Koen, Liezl, Botes, Willem C., Deleuze, J.F., Warnich, Louise
Format:	Artikel
Sprache:	eng
Schlagworte:	Abnormal involuntary movements Adult Adult and adolescent clinical studies Africa, Southern - epidemiology Africa, Southern - ethnology Alanine - genetics Biological and medical sciences Chi-Square Distribution Female Gene Frequency Genetic Predisposition to Disease Genotype Humans Male Medical sciences Middle Aged MnSOD Movement Disorders - epidemiology Movement Disorders - genetics Nervous system (semeiology, syndromes) Nervous system as a whole Neurology Neuropharmacology Pharmacology. Drug treatments Polymorphism, Genetic Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Psychoses Schizophrenia Schizophrenia - epidemiology Schizophrenia - genetics Superoxide Dismutase - genetics Tardive dyskinesia Valine - genetics Xhosa
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