MRI Evaluation of the Contralateral Breast in Women with Recently Diagnosed Breast Cancer
Up to 10% of women with a diagnosis of unilateral breast cancer have cancer in the contralateral breast, despite negative clinical and mammographic examinations. This study investigated the use of MRI examination of the contralateral breast in women with a diagnosis of unilateral breast cancer and n...
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| Veröffentlicht in: | The New England journal of medicine 2007-03, Vol.356 (13), p.1295-1303 |
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| container_title | The New England journal of medicine |
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| creator | Lehman, Constance D Gatsonis, Constantine Kuhl, Christiane K Hendrick, R. Edward Pisano, Etta D Hanna, Lucy Peacock, Sue Smazal, Stanley F Maki, Daniel D Julian, Thomas B DePeri, Elizabeth R Bluemke, David A Schnall, Mitchell D |
| description | Up to 10% of women with a diagnosis of unilateral breast cancer have cancer in the contralateral breast, despite negative clinical and mammographic examinations. This study investigated the use of MRI examination of the contralateral breast in women with a diagnosis of unilateral breast cancer and negative clinical and mammographic examinations. MRI detected occult cancer in the contralateral breast in about 3% of these women. All of the cancers were early stage, without evidence of spread to the lymph nodes or beyond.
MRI detected occult cancer in the contralateral breast in about 3% of women with a diagnosis of unilateral breast cancer and negative clinical and mammographic examinations.
A woman with unilateral breast cancer has an increased risk of having cancer in the contralateral breast.
1
–
6
In the 1990s, the role of mammography in improving the detection of contralateral cancers at the time of the initial diagnosis of breast cancer was firmly established; as compared with clinical breast examination alone, mammography resulted in a 1 to 3% increase in the number of cancers detected.
7
–
9
Despite normal findings on clinical and mammographic examination of the contralateral breast at the time of the initial breast-cancer diagnosis, however, contralateral cancer was subsequently detected in up to 10% of women.
1
, . . . |
| doi_str_mv | 10.1056/NEJMoa065447 |
| format | Article |
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MRI detected occult cancer in the contralateral breast in about 3% of women with a diagnosis of unilateral breast cancer and negative clinical and mammographic examinations.
A woman with unilateral breast cancer has an increased risk of having cancer in the contralateral breast.
1
–
6
In the 1990s, the role of mammography in improving the detection of contralateral cancers at the time of the initial diagnosis of breast cancer was firmly established; as compared with clinical breast examination alone, mammography resulted in a 1 to 3% increase in the number of cancers detected.
7
–
9
Despite normal findings on clinical and mammographic examination of the contralateral breast at the time of the initial breast-cancer diagnosis, however, contralateral cancer was subsequently detected in up to 10% of women.
1
, . . .</description><identifier>ISSN: 0028-4793</identifier><identifier>EISSN: 1533-4406</identifier><identifier>DOI: 10.1056/NEJMoa065447</identifier><identifier>PMID: 17392300</identifier><identifier>CODEN: NEJMAG</identifier><language>eng</language><publisher>Boston, MA: Massachusetts Medical Society</publisher><subject>Biological and medical sciences ; Biopsy ; Breast - pathology ; Breast cancer ; Breast Neoplasms - diagnosis ; Breast Neoplasms - diagnostic imaging ; Breast Neoplasms - pathology ; Carcinoma in Situ - diagnosis ; Carcinoma, Ductal, Breast - diagnosis ; Female ; Follow-Up Studies ; General aspects ; Gynecology. Andrology. Obstetrics ; Humans ; Magnetic Resonance Imaging ; Mammary gland diseases ; Mammography ; Medical diagnosis ; Medical sciences ; Middle Aged ; NMR ; Nuclear magnetic resonance ; Predictive Value of Tests ; ROC Curve ; Sensitivity and Specificity ; Tumors</subject><ispartof>The New England journal of medicine, 2007-03, Vol.356 (13), p.1295-1303</ispartof><rights>Copyright © 2007 Massachusetts Medical Society. All rights reserved.</rights><rights>2007 INIST-CNRS</rights><rights>Copyright 2007 Massachusetts Medical Society.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c504t-2a7f7fca843f4a1d74013810c4f6e49afdf7a291bd39c21e74155aee5c087643</citedby><cites>FETCH-LOGICAL-c504t-2a7f7fca843f4a1d74013810c4f6e49afdf7a291bd39c21e74155aee5c087643</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.nejm.org/doi/pdf/10.1056/NEJMoa065447$$EPDF$$P50$$Gmms$$H</linktopdf><linktohtml>$$Uhttps://www.nejm.org/doi/full/10.1056/NEJMoa065447$$EHTML$$P50$$Gmms$$H</linktohtml><link.rule.ids>314,776,780,2746,2747,26080,27901,27902,52357,54039</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=18624985$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17392300$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lehman, Constance D</creatorcontrib><creatorcontrib>Gatsonis, Constantine</creatorcontrib><creatorcontrib>Kuhl, Christiane K</creatorcontrib><creatorcontrib>Hendrick, R. Edward</creatorcontrib><creatorcontrib>Pisano, Etta D</creatorcontrib><creatorcontrib>Hanna, Lucy</creatorcontrib><creatorcontrib>Peacock, Sue</creatorcontrib><creatorcontrib>Smazal, Stanley F</creatorcontrib><creatorcontrib>Maki, Daniel D</creatorcontrib><creatorcontrib>Julian, Thomas B</creatorcontrib><creatorcontrib>DePeri, Elizabeth R</creatorcontrib><creatorcontrib>Bluemke, David A</creatorcontrib><creatorcontrib>Schnall, Mitchell D</creatorcontrib><creatorcontrib>ACRIN Trial 6667 Investigators Group</creatorcontrib><title>MRI Evaluation of the Contralateral Breast in Women with Recently Diagnosed Breast Cancer</title><title>The New England journal of medicine</title><addtitle>N Engl J Med</addtitle><description>Up to 10% of women with a diagnosis of unilateral breast cancer have cancer in the contralateral breast, despite negative clinical and mammographic examinations. This study investigated the use of MRI examination of the contralateral breast in women with a diagnosis of unilateral breast cancer and negative clinical and mammographic examinations. MRI detected occult cancer in the contralateral breast in about 3% of these women. All of the cancers were early stage, without evidence of spread to the lymph nodes or beyond.
MRI detected occult cancer in the contralateral breast in about 3% of women with a diagnosis of unilateral breast cancer and negative clinical and mammographic examinations.
A woman with unilateral breast cancer has an increased risk of having cancer in the contralateral breast.
1
–
6
In the 1990s, the role of mammography in improving the detection of contralateral cancers at the time of the initial diagnosis of breast cancer was firmly established; as compared with clinical breast examination alone, mammography resulted in a 1 to 3% increase in the number of cancers detected.
7
–
9
Despite normal findings on clinical and mammographic examination of the contralateral breast at the time of the initial breast-cancer diagnosis, however, contralateral cancer was subsequently detected in up to 10% of women.
1
, . . .</description><subject>Biological and medical sciences</subject><subject>Biopsy</subject><subject>Breast - pathology</subject><subject>Breast cancer</subject><subject>Breast Neoplasms - diagnosis</subject><subject>Breast Neoplasms - diagnostic imaging</subject><subject>Breast Neoplasms - pathology</subject><subject>Carcinoma in Situ - diagnosis</subject><subject>Carcinoma, Ductal, Breast - diagnosis</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>General aspects</subject><subject>Gynecology. Andrology. 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Edward</au><au>Pisano, Etta D</au><au>Hanna, Lucy</au><au>Peacock, Sue</au><au>Smazal, Stanley F</au><au>Maki, Daniel D</au><au>Julian, Thomas B</au><au>DePeri, Elizabeth R</au><au>Bluemke, David A</au><au>Schnall, Mitchell D</au><aucorp>ACRIN Trial 6667 Investigators Group</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>MRI Evaluation of the Contralateral Breast in Women with Recently Diagnosed Breast Cancer</atitle><jtitle>The New England journal of medicine</jtitle><addtitle>N Engl J Med</addtitle><date>2007-03-29</date><risdate>2007</risdate><volume>356</volume><issue>13</issue><spage>1295</spage><epage>1303</epage><pages>1295-1303</pages><issn>0028-4793</issn><eissn>1533-4406</eissn><coden>NEJMAG</coden><abstract>Up to 10% of women with a diagnosis of unilateral breast cancer have cancer in the contralateral breast, despite negative clinical and mammographic examinations. This study investigated the use of MRI examination of the contralateral breast in women with a diagnosis of unilateral breast cancer and negative clinical and mammographic examinations. MRI detected occult cancer in the contralateral breast in about 3% of these women. All of the cancers were early stage, without evidence of spread to the lymph nodes or beyond.
MRI detected occult cancer in the contralateral breast in about 3% of women with a diagnosis of unilateral breast cancer and negative clinical and mammographic examinations.
A woman with unilateral breast cancer has an increased risk of having cancer in the contralateral breast.
1
–
6
In the 1990s, the role of mammography in improving the detection of contralateral cancers at the time of the initial diagnosis of breast cancer was firmly established; as compared with clinical breast examination alone, mammography resulted in a 1 to 3% increase in the number of cancers detected.
7
–
9
Despite normal findings on clinical and mammographic examination of the contralateral breast at the time of the initial breast-cancer diagnosis, however, contralateral cancer was subsequently detected in up to 10% of women.
1
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| ispartof | The New England journal of medicine, 2007-03, Vol.356 (13), p.1295-1303 |
| issn | 0028-4793 1533-4406 |
| language | eng |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; New England Journal of Medicine |
| subjects | Biological and medical sciences Biopsy Breast - pathology Breast cancer Breast Neoplasms - diagnosis Breast Neoplasms - diagnostic imaging Breast Neoplasms - pathology Carcinoma in Situ - diagnosis Carcinoma, Ductal, Breast - diagnosis Female Follow-Up Studies General aspects Gynecology. Andrology. Obstetrics Humans Magnetic Resonance Imaging Mammary gland diseases Mammography Medical diagnosis Medical sciences Middle Aged NMR Nuclear magnetic resonance Predictive Value of Tests ROC Curve Sensitivity and Specificity Tumors |
| title | MRI Evaluation of the Contralateral Breast in Women with Recently Diagnosed Breast Cancer |
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