Use of statistical methods to find the polysaccharide structural characteristics and the relationships between monosaccharide composition ratio and macrophage stimulatory activity of regionally different strains of Lentinula edodes

Multiple linear regression analysis was used to deduce the correlation between the monosaccharide composition ratios of 10 regionally different strains of Lentinula edodes and their in vitro macrophage stimulatory activities. Arabinose, xylose, mannose and galactose were identified as the monosaccha...

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Veröffentlicht in:Analytica chimica acta 2007-02, Vol.584 (1), p.50-56
Hauptverfasser: Lo, Tiffany Chien Ting, Jiang, Yi Huei, Chao, Anne Lien Ju, Chang, Cheng Allen
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Jiang, Yi Huei
Chao, Anne Lien Ju
Chang, Cheng Allen
description Multiple linear regression analysis was used to deduce the correlation between the monosaccharide composition ratios of 10 regionally different strains of Lentinula edodes and their in vitro macrophage stimulatory activities. Arabinose, xylose, mannose and galactose were identified as the monosaccharides that could be related to macrophage stimulatory activities. Additional principal component analysis and factor analysis methods were used to treat the same monosaccharide composition ratio data and the compositions of arabinose, xylose, mannose and galactose were found to be important. Interestingly, glucose, although presented in large compositions in all strains presumably forms the backbone of the polysaccharide structures, is not selected as the determinant factor for either structural characteristics or that of the in vitro macrophage stimulatory activities.
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subjects Analytical chemistry
Animals
Cell Line
Chemistry
Exact sciences and technology
Factor analysis
Lentinula edodes
Macrophage stimulatory activity
Macrophages - drug effects
Macrophages - physiology
Mice
Mice, Inbred BALB C
Monosaccharides - analysis
Monosaccharides - pharmacology
Multiple linear regression analysis
Polysaccharide
Polysaccharides - chemistry
Polysaccharides - isolation & purification
Polysaccharides - pharmacology
Principal component analysis
Regression Analysis
Shiitake Mushrooms - chemistry
Shiitake Mushrooms - classification
title Use of statistical methods to find the polysaccharide structural characteristics and the relationships between monosaccharide composition ratio and macrophage stimulatory activity of regionally different strains of Lentinula edodes
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