Automated quantification of nuclear immunohistochemical markers with different complexity

Manual quantification of immunohistochemically stained nuclear markers is still laborious and subjective and the use of computerized systems for digital image analysis have not yet resolved the problems of nuclear clustering. In this study, we designed a new automatic procedure for quantifying vario...

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Veröffentlicht in:	Histochemistry and cell biology 2008-03, Vol.129 (3), p.379-387
Hauptverfasser:	López, Carlos, Lejeune, Marylène, Salvadó, María Teresa, Escrivà, Patricia, Bosch, Ramón, Pons, Lluis E., Álvaro, Tomás, Roig, Jordi, Cugat, Xavier, Baucells, Jordi, Jaén, Joaquín
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Automation Biochemistry Biomarkers, Tumor - analysis Biomedical and Life Sciences Biomedicine Cell Biology Cell Nucleus - chemistry Cell Nucleus - pathology Developmental Biology Digital imaging Histology Humans Image Processing, Computer-Assisted - methods Immunohistochemistry - methods Immunology Neoplasms - chemistry Neoplasms - pathology Original Paper Radioactive materials Reproducibility of Results Research methodology Software
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