Influence of iron on vitamin A nutritional status

Iron deficiency seems to deteriorate vitamin A metabolism leading to a reduction in serum retinol and an increase in hepatic retinol and retinyl ester. These alterations probably result from an increase in retinol sequestration to the liver and/or impairment in the activity of hepatic retinyl ester...

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Veröffentlicht in:	Nutrition reviews 2008-03, Vol.66 (3), p.141-147
Hauptverfasser:	Oliveira, J.M, Michelazzo, F.B, Stefanello, J, Rondó, P.H.C
Format:	Artikel
Sprache:	eng
Schlagworte:	Anemia, Iron-Deficiency - metabolism animal disease models Animals Biological and medical sciences Carboxylic Ester Hydrolases - metabolism dietary minerals dietary supplements Enzymes. Coenzymes. Vitamins. Pigments Fundamental and applied biological sciences. Psychology human nutrition Humans hydrolases interaction Iron Iron - blood iron deficiency anemia Liver Liver - enzymology Liver - metabolism metabolic sequestration Metabolism Metabolisms and neurohumoral controls micronutrients night blindness nutrient reserves nutrient-nutrient interactions Nutrition nutrition research Nutritional Status rats Vertebrates: anatomy and physiology, studies on body, several organs or systems Vitamin A Vitamin A - blood Vitamin A - metabolism vitamin deficiencies vitamin metabolism zinc
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Beschreibung
Zusammenfassung:	Iron deficiency seems to deteriorate vitamin A metabolism leading to a reduction in serum retinol and an increase in hepatic retinol and retinyl ester. These alterations probably result from an increase in retinol sequestration to the liver and/or impairment in the activity of hepatic retinyl ester hydrolases decreasing vitamin A mobilization.
ISSN:	0029-6643 1753-4887
DOI:	10.1111/j.1753-4887.2008.00018.x