Coregulators: transducing signal from transcription to alternative splicing

Cells respond to many external stimuli by modulating gene expression. A key step in this regulation is the control of transcription, which determines the concentrations of pre-mRNA that are produced. A second level of control involves maturation of pre-mRNAs; many are alternatively spliced, which ch...

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Veröffentlicht in:	Trends in endocrinology and metabolism 2007-04, Vol.18 (3), p.122-129
Hauptverfasser:	Auboeuf, Didier, Batsché, Eric, Dutertre, Martin, Muchardt, Christian, O’Malley, Bert W
Format:	Artikel
Sprache:	eng
Schlagworte:	Alternative Splicing - physiology Biological and medical sciences DNA Polymerase II - metabolism Endocrinology & Metabolism Fundamental and applied biological sciences. Psychology Genome, Human Humans Models, Biological Repressor Proteins - physiology Signal Transduction Trans-Activators - physiology Transcription, Genetic - physiology Vertebrates: endocrinology
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