Multiple Mesoderm Subsets Give Rise to Endothelial Cells, Whereas Hematopoietic Cells Are Differentiated Only from a Restricted Subset in Embryonic Stem Cell Differentiation Culture

In the developing mouse, vascular endothelial cell (EC) and hematopoietic cell (HPC) lineages are two initial cell lineages that diverge from mesodermal cells, which have been roughly subdivided into three subtypes according to their geographical location: the organizer, embryonic mesoderm in the pr...

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Veröffentlicht in:	Stem cells (Dayton, Ohio) Ohio), 2008-02, Vol.26 (2), p.401-411
Hauptverfasser:	Era, Takumi, Izumi, Naoki, Hayashi, Misato, Tada, Shinsuke, Nishikawa, Satomi, Nishikawa, Shin‐Ichi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bone Morphogenetic Protein 4 Bone Morphogenetic Proteins - pharmacology Brachyury Cell Differentiation - drug effects Cell Line Colony-Forming Units Assay Embryonic stem cell Embryonic Stem Cells - classification Embryonic Stem Cells - cytology Embryonic Stem Cells - metabolism Endothelial Cells - cytology Endothelial Cells - metabolism Fetal Proteins - genetics Goosecoid Green Fluorescent Proteins - genetics Hematopoiesis Hematopoietic Stem Cells - classification Hematopoietic Stem Cells - cytology Hematopoietic Stem Cells - metabolism Mesoderm - cytology Mesoderm - embryology Mesoderm - metabolism Mice Platelet‐derived growth factor receptor‐α Vascular endothelial growth factor receptor 2 Primitive Streak - cytology Primitive Streak - embryology Primitive Streak - metabolism Receptor, Platelet-Derived Growth Factor alpha - metabolism Recombinant Proteins - genetics T-Box Domain Proteins - genetics Vascular Endothelial Growth Factor Receptor-2 - metabolism
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