Predictors of long-term outcomes in patients after elective stent implantation for unprotected left main coronary artery disease
The purpose of this study was to investigate the predictor of long-term outcomes in patients after stent implantation for unprotected left main coronary artery (LMCA) disease. Coronary stenting has recently been advocated as an alternative procedure for LMCA disease. Information on the predictors of...
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| Veröffentlicht in: | Heart and vessels 2007-03, Vol.22 (2), p.99-103 |
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| creator | Lee, Ren-Jen Shih, Ko-Nien Lee, Shih-Huang Shyu, Kou-Gi Chiu, Chiung-Zuan Lin, Shen-Chang Hung, Huei-Fong Liou, Jer-Young Cheng, Jun-Jack Kuan, Peiliang |
| description | The purpose of this study was to investigate the predictor of long-term outcomes in patients after stent implantation for unprotected left main coronary artery (LMCA) disease. Coronary stenting has recently been advocated as an alternative procedure for LMCA disease. Information on the predictors of long-term outcomes in patients after stent implantation for unprotected LMCA disease is not clear. Seventy six patients (51 men and 25 women, age 68 +/- 10 years) with medically refractory angina received coronary stenting for unprotected LMCA disease. During a follow-up period of 40 +/- 26 months, 7 patients (9%) died because of cardiovascular disease in 5 (7%) and noncardiovascular disease in 2 (3%). In the other 69 patients, 19 patients (25%) needed repeated percutaneous coronary intervention (PCI) and/or coronary artery bypass grafting (CABG). In a univariate analysis, only female sex was related to the repeated PCI and/or CABG (P = 0.04). A history of cerebral vascular attack (CVA) (P = 0.005), anemia (P = 0.03) and lower left ventricular ejection fraction (LVEF) (P = 0.008) were related to the cardiovascular mortality. A history of myocardial infarction (P = 0.03), a history of CVA (P = 0.02), anemia (P = 0.02), and lower LVEF (P = 0.002) were related to the total mortality. In a multivariate analysis, female sex (P = 0.007; odds ratio 5.29, 95% confidence interval [CI] 1.57-17.80) and young age (P = 0.025; odds ratio 3.92, 95% CI 1.19-12.98) could predict the repeated PCI and/or CABG. Only a history of CVA could predict the cardiovascular mortality (P = 0.027; odds ratio 34.18, 95% CI 1.49-783) and only lower LVEF could predict the total mortality (P = 0.027; odds ratio 13.26, 95% CI 1.34-131). Female sex and young age could predict the repeated PCI and/or CABG in patients after stent implantation for unprotected LMCA disease. Furthermore, a history of CVA could predict the cardiovascular mortality and lower LVEF could predict the total mortality. |
| doi_str_mv | 10.1007/s00380-006-0948-7 |
| format | Article |
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Coronary stenting has recently been advocated as an alternative procedure for LMCA disease. Information on the predictors of long-term outcomes in patients after stent implantation for unprotected LMCA disease is not clear. Seventy six patients (51 men and 25 women, age 68 +/- 10 years) with medically refractory angina received coronary stenting for unprotected LMCA disease. During a follow-up period of 40 +/- 26 months, 7 patients (9%) died because of cardiovascular disease in 5 (7%) and noncardiovascular disease in 2 (3%). In the other 69 patients, 19 patients (25%) needed repeated percutaneous coronary intervention (PCI) and/or coronary artery bypass grafting (CABG). In a univariate analysis, only female sex was related to the repeated PCI and/or CABG (P = 0.04). A history of cerebral vascular attack (CVA) (P = 0.005), anemia (P = 0.03) and lower left ventricular ejection fraction (LVEF) (P = 0.008) were related to the cardiovascular mortality. A history of myocardial infarction (P = 0.03), a history of CVA (P = 0.02), anemia (P = 0.02), and lower LVEF (P = 0.002) were related to the total mortality. In a multivariate analysis, female sex (P = 0.007; odds ratio 5.29, 95% confidence interval [CI] 1.57-17.80) and young age (P = 0.025; odds ratio 3.92, 95% CI 1.19-12.98) could predict the repeated PCI and/or CABG. Only a history of CVA could predict the cardiovascular mortality (P = 0.027; odds ratio 34.18, 95% CI 1.49-783) and only lower LVEF could predict the total mortality (P = 0.027; odds ratio 13.26, 95% CI 1.34-131). Female sex and young age could predict the repeated PCI and/or CABG in patients after stent implantation for unprotected LMCA disease. Furthermore, a history of CVA could predict the cardiovascular mortality and lower LVEF could predict the total mortality.</description><identifier>ISSN: 0910-8327</identifier><identifier>EISSN: 1615-2573</identifier><identifier>DOI: 10.1007/s00380-006-0948-7</identifier><identifier>PMID: 17390204</identifier><identifier>CODEN: HEVEEO</identifier><language>eng</language><publisher>Japan: Springer Nature B.V</publisher><subject>Age Factors ; Aged ; Analysis of Variance ; Angioplasty, Balloon, Coronary ; Cardiovascular disease ; Clinical outcomes ; Coronary Artery Bypass ; Coronary Artery Disease - mortality ; Coronary Artery Disease - therapy ; Coronary Restenosis - therapy ; Coronary vessels ; Female ; Humans ; Male ; Middle Aged ; Prognosis ; Retreatment ; Risk Factors ; Sex Factors ; Stents ; Stroke Volume ; Transplants & implants ; Treatment Outcome</subject><ispartof>Heart and vessels, 2007-03, Vol.22 (2), p.99-103</ispartof><rights>Springer-Verlag Tokyo 2007</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c350t-cda49a51a30f8b35e26cf3cbcf677ada70dca77999aea802d36782c98c49a8163</citedby><cites>FETCH-LOGICAL-c350t-cda49a51a30f8b35e26cf3cbcf677ada70dca77999aea802d36782c98c49a8163</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17390204$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lee, Ren-Jen</creatorcontrib><creatorcontrib>Shih, Ko-Nien</creatorcontrib><creatorcontrib>Lee, Shih-Huang</creatorcontrib><creatorcontrib>Shyu, Kou-Gi</creatorcontrib><creatorcontrib>Chiu, Chiung-Zuan</creatorcontrib><creatorcontrib>Lin, Shen-Chang</creatorcontrib><creatorcontrib>Hung, Huei-Fong</creatorcontrib><creatorcontrib>Liou, Jer-Young</creatorcontrib><creatorcontrib>Cheng, Jun-Jack</creatorcontrib><creatorcontrib>Kuan, Peiliang</creatorcontrib><title>Predictors of long-term outcomes in patients after elective stent implantation for unprotected left main coronary artery disease</title><title>Heart and vessels</title><addtitle>Heart Vessels</addtitle><description>The purpose of this study was to investigate the predictor of long-term outcomes in patients after stent implantation for unprotected left main coronary artery (LMCA) disease. Coronary stenting has recently been advocated as an alternative procedure for LMCA disease. Information on the predictors of long-term outcomes in patients after stent implantation for unprotected LMCA disease is not clear. Seventy six patients (51 men and 25 women, age 68 +/- 10 years) with medically refractory angina received coronary stenting for unprotected LMCA disease. During a follow-up period of 40 +/- 26 months, 7 patients (9%) died because of cardiovascular disease in 5 (7%) and noncardiovascular disease in 2 (3%). In the other 69 patients, 19 patients (25%) needed repeated percutaneous coronary intervention (PCI) and/or coronary artery bypass grafting (CABG). In a univariate analysis, only female sex was related to the repeated PCI and/or CABG (P = 0.04). A history of cerebral vascular attack (CVA) (P = 0.005), anemia (P = 0.03) and lower left ventricular ejection fraction (LVEF) (P = 0.008) were related to the cardiovascular mortality. A history of myocardial infarction (P = 0.03), a history of CVA (P = 0.02), anemia (P = 0.02), and lower LVEF (P = 0.002) were related to the total mortality. In a multivariate analysis, female sex (P = 0.007; odds ratio 5.29, 95% confidence interval [CI] 1.57-17.80) and young age (P = 0.025; odds ratio 3.92, 95% CI 1.19-12.98) could predict the repeated PCI and/or CABG. Only a history of CVA could predict the cardiovascular mortality (P = 0.027; odds ratio 34.18, 95% CI 1.49-783) and only lower LVEF could predict the total mortality (P = 0.027; odds ratio 13.26, 95% CI 1.34-131). Female sex and young age could predict the repeated PCI and/or CABG in patients after stent implantation for unprotected LMCA disease. Furthermore, a history of CVA could predict the cardiovascular mortality and lower LVEF could predict the total mortality.</description><subject>Age Factors</subject><subject>Aged</subject><subject>Analysis of Variance</subject><subject>Angioplasty, Balloon, Coronary</subject><subject>Cardiovascular disease</subject><subject>Clinical outcomes</subject><subject>Coronary Artery Bypass</subject><subject>Coronary Artery Disease - mortality</subject><subject>Coronary Artery Disease - therapy</subject><subject>Coronary Restenosis - therapy</subject><subject>Coronary vessels</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Prognosis</subject><subject>Retreatment</subject><subject>Risk Factors</subject><subject>Sex Factors</subject><subject>Stents</subject><subject>Stroke Volume</subject><subject>Transplants & implants</subject><subject>Treatment Outcome</subject><issn>0910-8327</issn><issn>1615-2573</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNpdkc1KAzEUhYMotlYfwI0EF-6iN5POZLKU4h8UdKHrkGZuZMrMpCYZoTsf3ZQWBMniQvKdw8k9hFxyuOUA8i4CiBoYQMVAzWsmj8iUV7xkRSnFMZmC4sBqUcgJOYtxDcBLxdUpmXApFBQwn5Kft4BNa5MPkXpHOz98soShp35M1vcYaTvQjUktDilS4_IbxQ5tar-RxpRvadtvOjOkzPiBOh_oOGyCT5nBhnboEu1NNrE--MGELTUhm2xp00Y0Ec_JiTNdxIvDnJGPx4f3xTNbvj69LO6XzIoSErONmStTciPA1StRYlFZJ-zKukpK0xgJjTVSKqUMmhqKRlSyLqyqbZbVvBIzcrP3zdm-RoxJ92202OXo6MeoJQhe5JPB63_g2o9hyNk0V5UqOM_bmxG-h2zwMQZ0ehPaPv9Oc9C7bvS-G5270btu9E5zdTAeVz02f4pDGeIXCm2M9g</recordid><startdate>20070301</startdate><enddate>20070301</enddate><creator>Lee, Ren-Jen</creator><creator>Shih, Ko-Nien</creator><creator>Lee, Shih-Huang</creator><creator>Shyu, Kou-Gi</creator><creator>Chiu, Chiung-Zuan</creator><creator>Lin, Shen-Chang</creator><creator>Hung, Huei-Fong</creator><creator>Liou, Jer-Young</creator><creator>Cheng, Jun-Jack</creator><creator>Kuan, Peiliang</creator><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QO</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>MBDVC</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20070301</creationdate><title>Predictors of long-term outcomes in patients after elective stent implantation for unprotected left main coronary artery disease</title><author>Lee, Ren-Jen ; Shih, Ko-Nien ; Lee, Shih-Huang ; Shyu, Kou-Gi ; Chiu, Chiung-Zuan ; Lin, Shen-Chang ; Hung, Huei-Fong ; Liou, Jer-Young ; Cheng, Jun-Jack ; Kuan, Peiliang</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c350t-cda49a51a30f8b35e26cf3cbcf677ada70dca77999aea802d36782c98c49a8163</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Age Factors</topic><topic>Aged</topic><topic>Analysis of Variance</topic><topic>Angioplasty, Balloon, Coronary</topic><topic>Cardiovascular disease</topic><topic>Clinical outcomes</topic><topic>Coronary Artery Bypass</topic><topic>Coronary Artery Disease - mortality</topic><topic>Coronary Artery Disease - therapy</topic><topic>Coronary Restenosis - therapy</topic><topic>Coronary vessels</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Prognosis</topic><topic>Retreatment</topic><topic>Risk Factors</topic><topic>Sex Factors</topic><topic>Stents</topic><topic>Stroke Volume</topic><topic>Transplants & implants</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lee, Ren-Jen</creatorcontrib><creatorcontrib>Shih, Ko-Nien</creatorcontrib><creatorcontrib>Lee, Shih-Huang</creatorcontrib><creatorcontrib>Shyu, Kou-Gi</creatorcontrib><creatorcontrib>Chiu, Chiung-Zuan</creatorcontrib><creatorcontrib>Lin, Shen-Chang</creatorcontrib><creatorcontrib>Hung, Huei-Fong</creatorcontrib><creatorcontrib>Liou, Jer-Young</creatorcontrib><creatorcontrib>Cheng, Jun-Jack</creatorcontrib><creatorcontrib>Kuan, Peiliang</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Biotechnology Research Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Heart and vessels</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lee, Ren-Jen</au><au>Shih, Ko-Nien</au><au>Lee, Shih-Huang</au><au>Shyu, Kou-Gi</au><au>Chiu, Chiung-Zuan</au><au>Lin, Shen-Chang</au><au>Hung, Huei-Fong</au><au>Liou, Jer-Young</au><au>Cheng, Jun-Jack</au><au>Kuan, Peiliang</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Predictors of long-term outcomes in patients after elective stent implantation for unprotected left main coronary artery disease</atitle><jtitle>Heart and vessels</jtitle><addtitle>Heart Vessels</addtitle><date>2007-03-01</date><risdate>2007</risdate><volume>22</volume><issue>2</issue><spage>99</spage><epage>103</epage><pages>99-103</pages><issn>0910-8327</issn><eissn>1615-2573</eissn><coden>HEVEEO</coden><abstract>The purpose of this study was to investigate the predictor of long-term outcomes in patients after stent implantation for unprotected left main coronary artery (LMCA) disease. Coronary stenting has recently been advocated as an alternative procedure for LMCA disease. Information on the predictors of long-term outcomes in patients after stent implantation for unprotected LMCA disease is not clear. Seventy six patients (51 men and 25 women, age 68 +/- 10 years) with medically refractory angina received coronary stenting for unprotected LMCA disease. During a follow-up period of 40 +/- 26 months, 7 patients (9%) died because of cardiovascular disease in 5 (7%) and noncardiovascular disease in 2 (3%). In the other 69 patients, 19 patients (25%) needed repeated percutaneous coronary intervention (PCI) and/or coronary artery bypass grafting (CABG). In a univariate analysis, only female sex was related to the repeated PCI and/or CABG (P = 0.04). A history of cerebral vascular attack (CVA) (P = 0.005), anemia (P = 0.03) and lower left ventricular ejection fraction (LVEF) (P = 0.008) were related to the cardiovascular mortality. A history of myocardial infarction (P = 0.03), a history of CVA (P = 0.02), anemia (P = 0.02), and lower LVEF (P = 0.002) were related to the total mortality. In a multivariate analysis, female sex (P = 0.007; odds ratio 5.29, 95% confidence interval [CI] 1.57-17.80) and young age (P = 0.025; odds ratio 3.92, 95% CI 1.19-12.98) could predict the repeated PCI and/or CABG. Only a history of CVA could predict the cardiovascular mortality (P = 0.027; odds ratio 34.18, 95% CI 1.49-783) and only lower LVEF could predict the total mortality (P = 0.027; odds ratio 13.26, 95% CI 1.34-131). Female sex and young age could predict the repeated PCI and/or CABG in patients after stent implantation for unprotected LMCA disease. Furthermore, a history of CVA could predict the cardiovascular mortality and lower LVEF could predict the total mortality.</abstract><cop>Japan</cop><pub>Springer Nature B.V</pub><pmid>17390204</pmid><doi>10.1007/s00380-006-0948-7</doi><tpages>5</tpages></addata></record> |
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| subjects | Age Factors Aged Analysis of Variance Angioplasty, Balloon, Coronary Cardiovascular disease Clinical outcomes Coronary Artery Bypass Coronary Artery Disease - mortality Coronary Artery Disease - therapy Coronary Restenosis - therapy Coronary vessels Female Humans Male Middle Aged Prognosis Retreatment Risk Factors Sex Factors Stents Stroke Volume Transplants & implants Treatment Outcome |
| title | Predictors of long-term outcomes in patients after elective stent implantation for unprotected left main coronary artery disease |
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