Is cultured tendon fibroblast a good model to study tendon healing?

Cultured tendon fibroblasts (CTFs) from intact explants are widely used to study tendon healing in vitro. The significance of these findings may rely on similarities between CTFs and healing tendon fibroblasts in situ. Our purpose was to compare CTFs with fibroblasts cultured from healing tendons. W...

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Veröffentlicht in:	Journal of orthopaedic research 2008-03, Vol.26 (3), p.374-383
Hauptverfasser:	Fu, Sai-Chuen, Cheuk, Yau-Chuk, Chan, Kai-Ming, Hung, Leung-Kim, Wong, Margaret Wan-Nar
Format:	Artikel
Sprache:	eng
Schlagworte:	Actins - genetics Animals Cells, Cultured Extracellular Matrix Proteins - genetics Fibroblasts - drug effects Fibroblasts - metabolism healing tendon In Vitro Techniques Male Muscle, Smooth - metabolism Proliferating Cell Nuclear Antigen - metabolism Rats Rats, Sprague-Dawley Research Design - standards RNA, Messenger - metabolism tendon fibroblasts Tendon Injuries - metabolism Tendon Injuries - pathology Tendon Injuries - physiopathology Time Factors Transforming Growth Factor beta1 - pharmacology Wound Healing
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