common VLDLR polymorphism interacts with APOE genotype in the prediction of carotid artery disease risk

The genetic factors associated with carotid artery disease (CAAD) are not fully known. Because of its role in lipid metabolism, we hypothesized that common genetic variation in the very low density lipoprotein receptor (VLDLR) gene is associated with severe CAAD (>80% stenosis), body mass index (...

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Veröffentlicht in:	Journal of lipid research 2008-03, Vol.49 (3), p.588-596
Hauptverfasser:	Crawford, Dana C, Nord, Alex S, Badzioch, Michael D, Ranchalis, Jane, McKinstry, Laura A, Ahearn, Magdalena, Bertucci, Caterina, Shephard, Cynthia, Wong, Michelle, Rieder, Mark J, Schellenberg, Gerard D, Nickerson, Deborah A, Heagerty, Patrick J, Wijsman, Ellen M, Jarvik, Gail P
Format:	Artikel
Sprache:	eng
Schlagworte:	5' Flanking Region Apolipoproteins B Apolipoproteins E - genetics Body Mass Index Carotid Artery Diseases - genetics DNA Mutational Analysis Genetic Predisposition to Disease Genotype Humans Molecular Epidemiology Polymorphism, Single Nucleotide Receptors, LDL - genetics Risk Factors
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