Randomized double-blind study comparing the efficacy and safety of lamotrigine and amitriptyline in painful diabetic neuropathy

Aims To compare the efficacy and safety of lamotrigine and amitriptyline in controlling chronic painful peripheral neuropathy in diabetic patients. Methods A randomized, double‐blind, crossover, active‐control, clinical trial with variable dose titration was carried out (n = 53). Amitriptyline ora...

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Veröffentlicht in:	Diabetic medicine 2007-04, Vol.24 (4), p.377-383
Hauptverfasser:	Jose, V. M., Bhansali, A., Hota, D., Pandhi, P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Algorithms amitriptyline Amitriptyline - therapeutic use Analgesics, Non-Narcotic - therapeutic use Biological and medical sciences Calcium Channel Blockers - therapeutic use Cross-Over Studies diabetes Diabetes. Impaired glucose tolerance Diabetic Neuropathies - drug therapy Double-Blind Method Endocrine pancreas. Apud cells (diseases) Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance Female Humans lamotrigine Male Medical sciences Middle Aged neuropathy pain Pain Measurement Placebos Triazines - therapeutic use
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