Transcription Termination and RNA Degradation Contribute to Silencing of RNA Polymerase II Transcription within Heterochromatin

Within the heterochromatin of budding yeast, RNA polymerase II (RNAPII) transcription is repressed by the Sir2 deacetylase. Although heterochromatic silencing is generally thought to be due to limited accessibility of the underlying DNA, there are several reports of RNAPII and basal transcription fa...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Molecular cell 2008-02, Vol.29 (3), p.313-323
Hauptverfasser:	Vasiljeva, Lidia, Kim, Minkyu, Terzi, Nihal, Soares, Luis M., Buratowski, Stephen
Format:	Artikel
Sprache:	eng
Schlagworte:	DNA DNA, Ribosomal - analysis Gene Expression Regulation, Fungal Genes, Fungal Genes, Reporter Heterochromatin RNA Polymerase II - metabolism RNA Stability RNA, Fungal - metabolism Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae - metabolism Silent Information Regulator Proteins, Saccharomyces cerevisiae - genetics Silent Information Regulator Proteins, Saccharomyces cerevisiae - metabolism Transcription, Genetic
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!