Genetic aspects in attention-deficit/hyperactivity disorder
Summary Attention-deficit/hyperactivity disorder (ADHD) is a common psychiatric disorder among children and adolescents with high heritability. Molecular genetic findings support the thesis that dopaminergic, serotonergic, and noradrenergic neurotransmission pathways account for the etiology of this...
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Veröffentlicht in: | Journal of Neural Transmission 2008-02, Vol.115 (2), p.305-315 |
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creator | Albayrak, Ö. Friedel, S. Schimmelmann, B. G. Hinney, A. Hebebrand, J. |
description | Summary
Attention-deficit/hyperactivity disorder (ADHD) is a common psychiatric disorder among children and adolescents with high heritability. Molecular genetic findings support the thesis that dopaminergic, serotonergic, and noradrenergic neurotransmission pathways account for the etiology of this complex disease. Genetic research comprises formal genetic studies, candidate gene studies, linkage analyses, and recently large-scale genome wide association studies, gene-environement interaction studies, and pharmacogenetics. This article comprehensively reviews the latest findings on the genetics of ADHD. |
doi_str_mv | 10.1007/s00702-007-0839-9 |
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Attention-deficit/hyperactivity disorder (ADHD) is a common psychiatric disorder among children and adolescents with high heritability. Molecular genetic findings support the thesis that dopaminergic, serotonergic, and noradrenergic neurotransmission pathways account for the etiology of this complex disease. Genetic research comprises formal genetic studies, candidate gene studies, linkage analyses, and recently large-scale genome wide association studies, gene-environement interaction studies, and pharmacogenetics. This article comprehensively reviews the latest findings on the genetics of ADHD.</description><identifier>ISSN: 0300-9564</identifier><identifier>EISSN: 1435-1463</identifier><identifier>DOI: 10.1007/s00702-007-0839-9</identifier><identifier>PMID: 18200432</identifier><identifier>CODEN: JNTRF3</identifier><language>eng</language><publisher>Vienna: Springer-Verlag</publisher><subject>Animals ; Attention Deficit Disorder with Hyperactivity - genetics ; Genetics ; GPI-Linked Proteins ; Humans ; Medicine ; Medicine & Public Health ; Neural Cell Adhesion Molecules - genetics ; Neurology ; Neurosciences ; Psychiatry ; Review Article ; Risk Factors</subject><ispartof>Journal of Neural Transmission, 2008-02, Vol.115 (2), p.305-315</ispartof><rights>Springer-Verlag 2008</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c400t-952f47da1bccf8cc73bfbfc706f95a3cd9b6c956ba83840e69994acd57f9f2003</citedby><cites>FETCH-LOGICAL-c400t-952f47da1bccf8cc73bfbfc706f95a3cd9b6c956ba83840e69994acd57f9f2003</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00702-007-0839-9$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00702-007-0839-9$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18200432$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Albayrak, Ö.</creatorcontrib><creatorcontrib>Friedel, S.</creatorcontrib><creatorcontrib>Schimmelmann, B. G.</creatorcontrib><creatorcontrib>Hinney, A.</creatorcontrib><creatorcontrib>Hebebrand, J.</creatorcontrib><title>Genetic aspects in attention-deficit/hyperactivity disorder</title><title>Journal of Neural Transmission</title><addtitle>J Neural Transm</addtitle><addtitle>J Neural Transm (Vienna)</addtitle><description>Summary
Attention-deficit/hyperactivity disorder (ADHD) is a common psychiatric disorder among children and adolescents with high heritability. Molecular genetic findings support the thesis that dopaminergic, serotonergic, and noradrenergic neurotransmission pathways account for the etiology of this complex disease. Genetic research comprises formal genetic studies, candidate gene studies, linkage analyses, and recently large-scale genome wide association studies, gene-environement interaction studies, and pharmacogenetics. This article comprehensively reviews the latest findings on the genetics of ADHD.</description><subject>Animals</subject><subject>Attention Deficit Disorder with Hyperactivity - genetics</subject><subject>Genetics</subject><subject>GPI-Linked Proteins</subject><subject>Humans</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Neural Cell Adhesion Molecules - genetics</subject><subject>Neurology</subject><subject>Neurosciences</subject><subject>Psychiatry</subject><subject>Review Article</subject><subject>Risk Factors</subject><issn>0300-9564</issn><issn>1435-1463</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEFLAzEQhYMoWqs_wIsUD95iJ5vsboInKVqFghc9h2w20ZR2d02yQv-9WbZQEMTLJDDfvHnzELoicEcAynlIBTKcKgZOBRZHaEIYzTFhBT1GE6AAWOQFO0PnIawBgJCSn6IzwjMARrMJul-axkSnZyp0Rscwc81MxWia6NoG18Y67eL8c9cZr3R03y7uZrULra-Nv0AnVm2Cudy_U_T-9Pi2eMar1-XL4mGFNQOIyUBmWVkrUmltudYlrWxldQmFFbmiuhZVoZPLSnHKGZhCCMGUrvPSCpt80im6HXU73371JkS5dUGbzUY1pu2DLNOdBef5vyARBRAueAJvfoHrtvdNOkJmKSGacTKsJSOkfRuCN1Z23m2V30kCcshfjvnL4TvkL0Waud4L99XW1IeJfeAJyEYgpFbzYfxh89-qP5jQj_I</recordid><startdate>20080201</startdate><enddate>20080201</enddate><creator>Albayrak, Ö.</creator><creator>Friedel, S.</creator><creator>Schimmelmann, B. G.</creator><creator>Hinney, A.</creator><creator>Hebebrand, J.</creator><general>Springer-Verlag</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>7TK</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope></search><sort><creationdate>20080201</creationdate><title>Genetic aspects in attention-deficit/hyperactivity disorder</title><author>Albayrak, Ö. ; Friedel, S. ; Schimmelmann, B. G. ; Hinney, A. ; Hebebrand, J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c400t-952f47da1bccf8cc73bfbfc706f95a3cd9b6c956ba83840e69994acd57f9f2003</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Animals</topic><topic>Attention Deficit Disorder with Hyperactivity - genetics</topic><topic>Genetics</topic><topic>GPI-Linked Proteins</topic><topic>Humans</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Neural Cell Adhesion Molecules - genetics</topic><topic>Neurology</topic><topic>Neurosciences</topic><topic>Psychiatry</topic><topic>Review Article</topic><topic>Risk Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Albayrak, Ö.</creatorcontrib><creatorcontrib>Friedel, S.</creatorcontrib><creatorcontrib>Schimmelmann, B. G.</creatorcontrib><creatorcontrib>Hinney, A.</creatorcontrib><creatorcontrib>Hebebrand, J.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Neurosciences Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of Neural Transmission</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Albayrak, Ö.</au><au>Friedel, S.</au><au>Schimmelmann, B. G.</au><au>Hinney, A.</au><au>Hebebrand, J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Genetic aspects in attention-deficit/hyperactivity disorder</atitle><jtitle>Journal of Neural Transmission</jtitle><stitle>J Neural Transm</stitle><addtitle>J Neural Transm (Vienna)</addtitle><date>2008-02-01</date><risdate>2008</risdate><volume>115</volume><issue>2</issue><spage>305</spage><epage>315</epage><pages>305-315</pages><issn>0300-9564</issn><eissn>1435-1463</eissn><coden>JNTRF3</coden><abstract>Summary
Attention-deficit/hyperactivity disorder (ADHD) is a common psychiatric disorder among children and adolescents with high heritability. Molecular genetic findings support the thesis that dopaminergic, serotonergic, and noradrenergic neurotransmission pathways account for the etiology of this complex disease. Genetic research comprises formal genetic studies, candidate gene studies, linkage analyses, and recently large-scale genome wide association studies, gene-environement interaction studies, and pharmacogenetics. This article comprehensively reviews the latest findings on the genetics of ADHD.</abstract><cop>Vienna</cop><pub>Springer-Verlag</pub><pmid>18200432</pmid><doi>10.1007/s00702-007-0839-9</doi><tpages>11</tpages></addata></record> |
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subjects | Animals Attention Deficit Disorder with Hyperactivity - genetics Genetics GPI-Linked Proteins Humans Medicine Medicine & Public Health Neural Cell Adhesion Molecules - genetics Neurology Neurosciences Psychiatry Review Article Risk Factors |
title | Genetic aspects in attention-deficit/hyperactivity disorder |
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