Genetic aspects in attention-deficit/hyperactivity disorder

Summary Attention-deficit/hyperactivity disorder (ADHD) is a common psychiatric disorder among children and adolescents with high heritability. Molecular genetic findings support the thesis that dopaminergic, serotonergic, and noradrenergic neurotransmission pathways account for the etiology of this...

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Veröffentlicht in:Journal of Neural Transmission 2008-02, Vol.115 (2), p.305-315
Hauptverfasser: Albayrak, Ö., Friedel, S., Schimmelmann, B. G., Hinney, A., Hebebrand, J.
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container_title Journal of Neural Transmission
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creator Albayrak, Ö.
Friedel, S.
Schimmelmann, B. G.
Hinney, A.
Hebebrand, J.
description Summary Attention-deficit/hyperactivity disorder (ADHD) is a common psychiatric disorder among children and adolescents with high heritability. Molecular genetic findings support the thesis that dopaminergic, serotonergic, and noradrenergic neurotransmission pathways account for the etiology of this complex disease. Genetic research comprises formal genetic studies, candidate gene studies, linkage analyses, and recently large-scale genome wide association studies, gene-environement interaction studies, and pharmacogenetics. This article comprehensively reviews the latest findings on the genetics of ADHD.
doi_str_mv 10.1007/s00702-007-0839-9
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subjects Animals
Attention Deficit Disorder with Hyperactivity - genetics
Genetics
GPI-Linked Proteins
Humans
Medicine
Medicine & Public Health
Neural Cell Adhesion Molecules - genetics
Neurology
Neurosciences
Psychiatry
Review Article
Risk Factors
title Genetic aspects in attention-deficit/hyperactivity disorder
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