Long-term lymphoma survivors following high-dose chemotherapy and autograft: Evidence of permanent telomere shortening in myeloid cells, associated with marked reduction of bone marrow hematopoietic stem cell reservoir

Objective To investigate telomere length (TL) and hematopoietic progenitors in long-term survivors after high-dose chemotherapy and peripheral blood stem cell (PBSC) autograft. Methods Peripheral blood (PB) and bone marrow (BM) samples were obtained from 31 subjects in continuous complete remission...

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Veröffentlicht in:Experimental hematology 2007-04, Vol.35 (4), p.673-681
Hauptverfasser: Rocci, Alberto, Ricca, Irene, Dellacasa, Chiara, Longoni, Paolo, Compagno, Mara, Francese, Roberto, Lobetti Bodoni, Chiara, Manzini, Paola, Caracciolo, Daniele, Boccadoro, Mario, Ferrero, Dario, Ladetto, Marco, Carlo-Stella, Carmelo, Tarella, Corrado
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Sprache:eng
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