Intramyocardial injection of vascular endothelial growth factor gene improves cardiac performance and inhibits cardiomyocyte apoptosis

Background: Previous studies suggest that vascular endothelial growth factor (VEGF) is a regulator of naturally occurring angiogenesis. However, whether VEGF plays a role in cardiomyocyte apoptosis is not known. Aim: To investigate the effects of intramyocardial injection of VEGF165 cDNA on cardiac...

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Veröffentlicht in:	European journal of heart failure 2007-04, Vol.9 (4), p.343-351
Hauptverfasser:	Ruixing, Yin, Dezhai, Yang, Hai, Wu, Kai, Huang, Xianghong, Wu, Yuming, Chen
Format:	Artikel
Sprache:	eng
Schlagworte:	angiogenesis Animals Apoptosis DNA, Complementary Gene Expression gene therapy Genetic Therapy heart failure Heart Failure - etiology Heart Failure - physiopathology Immunohistochemistry Male Muscle Cells Myocardial Infarction Myocardial Ischemia Myocardium - cytology Myocardium - metabolism Rats Rats, Sprague-Dawley Vascular Endothelial Growth Factor A - genetics Vascular Endothelial Growth Factor A - metabolism vascular endothelial growth factors
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