RanBP10 acts as a novel coactivator for the androgen receptor

Androgen receptor (AR) acts as a ligand-activated transcription factor that regulates the expression of genes involved in prostate development and tumorigenesis. RanBP10 shares significant amino acid sequence similarity with RanBPM that is a well-known AR coactivator. Here, we demonstrate that RanBP...

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Veröffentlicht in:	Biochemical and biophysical research communications 2008-03, Vol.368 (1), p.121-125
Hauptverfasser:	Harada, Naoki, Yokoyama, Tsuyoshi, Yamaji, Ryoichi, Nakano, Yoshihisa, Inui, Hiroshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Androgen receptor Animals Cell Line Cercopithecus aethiops Coactivator Glucocorticoid receptor Humans Nuclear receptor Prostate Protein Binding ran GTP-Binding Protein - genetics ran GTP-Binding Protein - metabolism RanBP10 RanBPM Receptors, Androgen - genetics Receptors, Androgen - metabolism Receptors, Glucocorticoid - metabolism Steroid hormone Transcriptional Activation - genetics
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