Kinetic analysis of a complete poxvirus transcriptome reveals an immediate-early class of genes

Vaccinia virus is the prototypic orthopoxvirus and was the vaccine used to eradicate smallpox, yet the expression profiles of many of its genes remain unknown. Using a genome tiling array approach, we simultaneously measured the expression levels of all 223 annotated vaccinia virus genes during infe...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2008-02, Vol.105 (6), p.2140-2145
Hauptverfasser:	Assarsson, Erika, Greenbaum, Jason A, Sundström, Magnus, Schaffer, Lana, Hammond, Jennifer A, Pasquetto, Valerie, Oseroff, Carla, Hendrickson, R. Curtis, Lefkowitz, Elliot J, Tscharke, David C, Sidney, John, Grey, Howard M, Head, Steven R, Peters, Bjoern, Sette, Alessandro
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological Sciences Gene expression Gene Expression Profiling Genes Genes, Immediate-Early Genes, Viral Genomes Genomics HeLa Cells Humans Infections Kinetics Multigene Family Open Reading Frames Orthopoxvirus Poxviridae - genetics Poxvirus Reverse Transcriptase Polymerase Chain Reaction RNA RNA, Messenger - genetics Tiling Transcription, Genetic Vaccinia virus Viruses
Online-Zugang:	Volltext
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