Pathogenesis of calciphylaxis: Hans Selye to nuclear factor κ-B

The clinical syndrome of calciphylaxis is characterized by arteriolar medial calcification, thrombotic cutaneous ischemia, necrotic skin ulceration, and a high mortality rate. This review integrates calciphylaxis risk factors with the molecular processes governing osseous and extraosseous mineraliza...

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Veröffentlicht in:	Journal of the American Academy of Dermatology 2008-03, Vol.58 (3), p.458-471
1. Verfasser:	Weenig, Roger H., MD, MPH
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Bone Resorption - metabolism Calcification, Physiologic Calciphylaxis - etiology Calciphylaxis - history Calciphylaxis - metabolism Calciphylaxis - therapy Calcium - metabolism Dermatology History, 20th Century Humans Ligands Medical sciences NF-kappa B - metabolism Parathyroid Hormone - metabolism Phosphates - metabolism Receptors, Cell Surface - metabolism SElye United States Vascular Diseases - etiology
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