Muscarinic cholinoceptor-stimulated phosphatidyl inositol pathway in corneal epithelial and endothelial cells

Muscarinic cholinoceptors are distributed widely in both the central and peripheral nervous system. The presence of muscarinic cholinoceptors in corneal tissue is well established. Previous reports have shown that corneal muscarinic cholinoceptors are of the m2 or m4 subtype. However, recent studies...

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Veröffentlicht in:	Graefe's archive for clinical and experimental ophthalmology 2007-04, Vol.245 (4), p.595-599
Hauptverfasser:	Grueb, Matthias, Mielke, Joerg, Bartz-Schmidt, Karl Ulrich, Rohrbach, Jens Martin
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholine - pharmacology Animals Cattle Dose-Response Relationship, Drug Endothelium, Corneal - drug effects Endothelium, Corneal - metabolism Epithelium, Corneal - drug effects Epithelium, Corneal - metabolism Fluorescent Antibody Technique, Indirect Inositol 1,4,5-Trisphosphate - metabolism Ophthalmology Phosphatidylinositol 4,5-Diphosphate - metabolism Protein Kinase C - metabolism Receptor, Muscarinic M5 - metabolism
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