Primary Nasal Epithelium Exposed to House Dust Mite Extract Shows Activated Expression in Allergic Individuals

Nasal epithelial cells form the outermost protective layer against environmental factors. However, this defense is not just physical; it has been shown that epithelial cells respond by the production of inflammatory mediators that may affect local immune responses. In this research we set out to cha...

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Veröffentlicht in:	American journal of respiratory cell and molecular biology 2008-03, Vol.38 (3), p.293-299
Hauptverfasser:	Vroling, Aram B, Jonker, Martijs J, Luiten, Silvia, Breit, Timo M, Fokkens, Wytske J, van Drunen, Cornelis M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Allergens - immunology Animals Case-Control Studies Cell Culture Techniques Cells, Cultured Cluster Analysis Down-Regulation - drug effects Epithelial Cells - immunology Gene Expression Humans Middle Aged Nasal Mucosa - cytology Nasal Provocation Tests NF-kappa B - immunology NF-kappa B - metabolism Oligonucleotide Array Sequence Analysis Principal Component Analysis Pyroglyphidae - immunology Reproducibility of Results RNA - genetics RNA - isolation & purification Skin Tests Time Factors Transcription Factor AP-1 - immunology Transcription Factor AP-1 - metabolism
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