Can matrix metalloproteinase inhibitors provide a realistic therapy in cardiovascular medicine?

Tissue matrix biology has provided potential new mechanisms to control vascular and cardiac ageing if effective means of modifying its control processes can be developed. Changing patterns of matrix composition are well documented in a range of cardiovascular disease processes. Locally active metall...

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Veröffentlicht in:	Current opinion in pharmacology 2007-04, Vol.7 (2), p.171-178
1. Verfasser:	MacFadyen, Robert J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cardiovascular Diseases - drug therapy Cardiovascular Diseases - physiopathology Drug Delivery Systems Enzyme Inhibitors - pharmacology Extracellular Matrix - drug effects Extracellular Matrix - metabolism Humans Internal Medicine Matrix Metalloproteinase Inhibitors Matrix Metalloproteinases - metabolism Medical Education Neovascularization, Physiologic Tissue Inhibitor of Metalloproteinases - physiology
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