Sulphidoleukotriene release of cord blood basophils in response to allergen stimulation correlates with neither a family history of atopy nor a subsequent development of atopic eczema

Summary Objective We tested a possible relationship between sulphidoleukotriene (SLT) release of cord blood (CB) basophils, a family history of atopy (HA) and subsequent development of atopic eczema. Population and methods A cohort of 86 neonates were involved (48.8% males; 46.5% with a positive HA+...

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Veröffentlicht in:	Clinical and experimental allergy 2008-03, Vol.38 (3), p.458-465
Hauptverfasser:	Walaschek, C., Heinzmann, A., Weckmann, M., Kopp, M. V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Allergens - immunology Allergic diseases allergy atopic eczema atopy Basophils - immunology Basophils - metabolism Biological and medical sciences Cohort Studies cord blood Dermatitis, Atopic - etiology Enzyme-Linked Immunosorbent Assay Female Fetal Blood - cytology Flow Cytometry Fundamental and applied biological sciences. Psychology Fundamental immunology Humans Hypersensitivity, Immediate - genetics Immunopathology Infant, Newborn Interferon-gamma - metabolism Interleukin-13 - metabolism Leukotrienes - metabolism Male Medical Records Medical sciences Osmolar Concentration Skin allergic diseases. Stinging insect allergies sulphidoleukotrienes Surveys and Questionnaires
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